Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple

Abstract We report the case of a 36‐year‐old patient who was initially managed for gynecomastia. The first biological analyses showed a moderately elevated alpha‐fetoprotein (AFP) level. After an endocrine etiology was excluded, an abdominal computed tomography scan showed typical focal nodular hype...

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Autores principales:	Paul Carrier, Anne Guyot, Marilyne Debette‐Gratien, Fabien Fredon, Marie‐Pierre Teissier, François Labrousse, Véronique Loustaud‐Ratti
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	hepatology liver imaging liver tumors Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/aa96001a8ae64f198e8125608e795b71
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spelling	oai:doaj.org-article:aa96001a8ae64f198e8125608e795b712021-11-18T11:25:44ZAlpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple2397-907010.1002/jgh3.12669https://doaj.org/article/aa96001a8ae64f198e8125608e795b712021-11-01T00:00:00Zhttps://doi.org/10.1002/jgh3.12669https://doaj.org/toc/2397-9070Abstract We report the case of a 36‐year‐old patient who was initially managed for gynecomastia. The first biological analyses showed a moderately elevated alpha‐fetoprotein (AFP) level. After an endocrine etiology was excluded, an abdominal computed tomography scan showed typical focal nodular hyperplasia (FNH) proven by biopsy and showing expression of AFP in FNH cells. After follow‐up for 24 months, the serum AFP and liver radiology remained unchanged. The association between an elevated AFP and FNH is rarely described in the medical literature.Paul CarrierAnne GuyotMarilyne Debette‐GratienFabien FredonMarie‐Pierre TeissierFrançois LabrousseVéronique Loustaud‐RattiWileyarticlehepatologyliver imagingliver tumorsDiseases of the digestive system. GastroenterologyRC799-869ENJGH Open, Vol 5, Iss 11, Pp 1316-1318 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	hepatology liver imaging liver tumors Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	hepatology liver imaging liver tumors Diseases of the digestive system. Gastroenterology RC799-869 Paul Carrier Anne Guyot Marilyne Debette‐Gratien Fabien Fredon Marie‐Pierre Teissier François Labrousse Véronique Loustaud‐Ratti Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple
description	Abstract We report the case of a 36‐year‐old patient who was initially managed for gynecomastia. The first biological analyses showed a moderately elevated alpha‐fetoprotein (AFP) level. After an endocrine etiology was excluded, an abdominal computed tomography scan showed typical focal nodular hyperplasia (FNH) proven by biopsy and showing expression of AFP in FNH cells. After follow‐up for 24 months, the serum AFP and liver radiology remained unchanged. The association between an elevated AFP and FNH is rarely described in the medical literature.
format	article
author	Paul Carrier Anne Guyot Marilyne Debette‐Gratien Fabien Fredon Marie‐Pierre Teissier François Labrousse Véronique Loustaud‐Ratti
author_facet	Paul Carrier Anne Guyot Marilyne Debette‐Gratien Fabien Fredon Marie‐Pierre Teissier François Labrousse Véronique Loustaud‐Ratti
author_sort	Paul Carrier
title	Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple
title_short	Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple
title_full	Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple
title_fullStr	Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple
title_full_unstemmed	Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple
title_sort	alpha‐fetoprotein and focal nodular hyperplasia: an unconventional couple
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/aa96001a8ae64f198e8125608e795b71
work_keys_str_mv	AT paulcarrier alphafetoproteinandfocalnodularhyperplasiaanunconventionalcouple AT anneguyot alphafetoproteinandfocalnodularhyperplasiaanunconventionalcouple AT marilynedebettegratien alphafetoproteinandfocalnodularhyperplasiaanunconventionalcouple AT fabienfredon alphafetoproteinandfocalnodularhyperplasiaanunconventionalcouple AT mariepierreteissier alphafetoproteinandfocalnodularhyperplasiaanunconventionalcouple AT francoislabrousse alphafetoproteinandfocalnodularhyperplasiaanunconventionalcouple AT veroniqueloustaudratti alphafetoproteinandfocalnodularhyperplasiaanunconventionalcouple
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Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple

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