PSYCHOTIC DISORDERS IN PEOPLE USING SYNTHETIC CANNABINOIDS (SPICE)
The study involved the group of patients (n = 40) with psychotic disorders who used synthetic cannabinoids (spice). Among the psychotic disorders according to ICD-10 we allocated intoxication delirium (F12.03; 35 %), schizophreniform disorder (F12.50; 60 %), disorder with predominantly manic psychot...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
Scientific Сentre for Family Health and Human Reproduction Problems
2017
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/aa9b126a2898407c98d0c842d2ba8b4f |
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| Sumario: | The study involved the group of patients (n = 40) with psychotic disorders who used synthetic cannabinoids (spice). Among the psychotic disorders according to ICD-10 we allocated intoxication delirium (F12.03; 35 %), schizophreniform disorder (F12.50; 60 %), disorder with predominantly manic psychotic symptoms (F12.55; 5 %). The average age of patients was 25.2 ± 4.4 years. Hereditary aggravation in patients who consume synthetic cannabinoids was presented by alcoholism and substance abuse (20 %), affective disorders (7.5 %), schizophrenia (5 %); personality disorders (10 %); suicides (2.5 %). The group of patients with intoxication with delirium had significantly higher frequency of family history of alcoholism and addiction to psychoactive substances compared with patients with schizophreniform disorder (p < 0.02). Clinic intoxication delirium was characterized by disturbance of consciousness (delirium, twilight) lasting from several hours to 2-3 days, psychomotor agitation, aggression, shouting certain phrases and words, anxiety, fear, visual hallucinations. In patients with acute schizophreniform disorder (24 patients; 60 %) symptoms consisted of a dominant affect (depressive, or mixed), productive psychopathological symptoms within the list of F20 headings of ICD-10. Productive syndromes were limited to verbal hallucinosis (true or its limiting variants) in the form of voiced (which discuss the patient's behavior, threaten him/her with death, offer advice), reference of persecutory delusion. The coming out of a psychotic state was characterized by short-term postpsychotic depression. Patients received detoxification therapy and also combined psychopharmacotherapy with the use of antipsychotics, antidepressants, tranquilizers, normotymics, nootropics. |
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