Structural basis of host protein hijacking in human T-cell leukemia virus integration

Structural basis of host protein hijacking in human T-cell leukemia virus integration

Integration of the reverse-transcribed viral DNA into host chromosomes is a critical step in the life-cycle of retroviruses such as the human T-cell leukemia virus type-1 (HTLV-1). Here the authors describe the structural role of the host co-factor protein phosphatase 2A B56γ subunit in supporting i...

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Main Authors: Veer Bhatt, Ke Shi, Daniel J. Salamango, Nicholas H. Moeller, Krishan K. Pandey, Sibes Bera, Thomas E. Bohl, Fredy Kurniawan, Kayo Orellana, Wei Zhang, Duane P. Grandgenett, Reuben S. Harris, Anna C. Sundborger-Lunna, Hideki Aihara
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/aa9b53faafb14e34a356550f154c5e2f
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https://doaj.org/article/aa9b53faafb14e34a356550f154c5e2f

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