Acrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk

Acrylamide in food is formed by the Maillard reaction. Numerous studies have shown that acrylamide is a neurotoxic and carcinogenic compound. The aim of this study was to determine the level of acrylamide in breast milk at different lactation stages and to evaluate the impact of breastfeeding women’...

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Autores principales:	Hanna Mojska, Iwona Gielecińska, Joanna Winiarek, Włodzimierz Sawicki
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	breast milk acrylamide LC–MS/MS infants exposure Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/aaa5a786c46a472ea5ae43013c8ea85c
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spelling	oai:doaj.org-article:aaa5a786c46a472ea5ae43013c8ea85c2021-11-25T19:08:13ZAcrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk10.3390/toxics91102982305-6304https://doaj.org/article/aaa5a786c46a472ea5ae43013c8ea85c2021-11-01T00:00:00Zhttps://www.mdpi.com/2305-6304/9/11/298https://doaj.org/toc/2305-6304Acrylamide in food is formed by the Maillard reaction. Numerous studies have shown that acrylamide is a neurotoxic and carcinogenic compound. The aim of this study was to determine the level of acrylamide in breast milk at different lactation stages and to evaluate the impact of breastfeeding women’s diet on the content of this compound in breast milk. The acrylamide level in breast milk samples was determined by LC–MS/MS. Breastfeeding women’s diet was evaluated based on the 24 h dietary recall. The median acrylamide level in colostrum (n = 47) was significantly (<i>p</i> < 0.0005) lower than in the mature milk (n = 26)—0.05 µg/L and 0.14 µg/L, respectively. The estimated breastfeeding women’s acrylamide intake from the hospital diet was significantly (<i>p</i> < 0.0001) lower than that from the home diet. We found positive—although modest and borderline significant—correlation between acrylamide intake by breastfeeding women from the hospital diet µg/day) and acrylamide level in the colostrum (µg/L). Acrylamide has been detected in human milk samples, and a positive correlation between dietary acrylamide intake by breastfeeding women and its content in breast milk was observed, which suggests that the concentration can be reduced. Breastfeeding women should avoid foods that may be a source of acrylamide in their diet.Hanna MojskaIwona GielecińskaJoanna WiniarekWłodzimierz SawickiMDPI AGarticlebreast milkacrylamideLC–MS/MSinfantsexposureChemical technologyTP1-1185ENToxics, Vol 9, Iss 298, p 298 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	breast milk acrylamide LC–MS/MS infants exposure Chemical technology TP1-1185
spellingShingle	breast milk acrylamide LC–MS/MS infants exposure Chemical technology TP1-1185 Hanna Mojska Iwona Gielecińska Joanna Winiarek Włodzimierz Sawicki Acrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk
description	Acrylamide in food is formed by the Maillard reaction. Numerous studies have shown that acrylamide is a neurotoxic and carcinogenic compound. The aim of this study was to determine the level of acrylamide in breast milk at different lactation stages and to evaluate the impact of breastfeeding women’s diet on the content of this compound in breast milk. The acrylamide level in breast milk samples was determined by LC–MS/MS. Breastfeeding women’s diet was evaluated based on the 24 h dietary recall. The median acrylamide level in colostrum (n = 47) was significantly (<i>p</i> < 0.0005) lower than in the mature milk (n = 26)—0.05 µg/L and 0.14 µg/L, respectively. The estimated breastfeeding women’s acrylamide intake from the hospital diet was significantly (<i>p</i> < 0.0001) lower than that from the home diet. We found positive—although modest and borderline significant—correlation between acrylamide intake by breastfeeding women from the hospital diet µg/day) and acrylamide level in the colostrum (µg/L). Acrylamide has been detected in human milk samples, and a positive correlation between dietary acrylamide intake by breastfeeding women and its content in breast milk was observed, which suggests that the concentration can be reduced. Breastfeeding women should avoid foods that may be a source of acrylamide in their diet.
format	article
author	Hanna Mojska Iwona Gielecińska Joanna Winiarek Włodzimierz Sawicki
author_facet	Hanna Mojska Iwona Gielecińska Joanna Winiarek Włodzimierz Sawicki
author_sort	Hanna Mojska
title	Acrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk
title_short	Acrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk
title_full	Acrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk
title_fullStr	Acrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk
title_full_unstemmed	Acrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk
title_sort	acrylamide content in breast milk: the evaluation of the impact of breastfeeding women’s diet and the estimation of the exposure of breastfed infants to acrylamide in breast milk
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/aaa5a786c46a472ea5ae43013c8ea85c
work_keys_str_mv	AT hannamojska acrylamidecontentinbreastmilktheevaluationoftheimpactofbreastfeedingwomensdietandtheestimationoftheexposureofbreastfedinfantstoacrylamideinbreastmilk AT iwonagielecinska acrylamidecontentinbreastmilktheevaluationoftheimpactofbreastfeedingwomensdietandtheestimationoftheexposureofbreastfedinfantstoacrylamideinbreastmilk AT joannawiniarek acrylamidecontentinbreastmilktheevaluationoftheimpactofbreastfeedingwomensdietandtheestimationoftheexposureofbreastfedinfantstoacrylamideinbreastmilk AT włodzimierzsawicki acrylamidecontentinbreastmilktheevaluationoftheimpactofbreastfeedingwomensdietandtheestimationoftheexposureofbreastfedinfantstoacrylamideinbreastmilk
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Acrylamide Content in Breast Milk: The Evaluation of the Impact of Breastfeeding Women’s Diet and the Estimation of the Exposure of Breastfed Infants to Acrylamide in Breast Milk

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