Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia

Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia

Abstract Hydatidiform moles are known to pose an extremely high risk of severe early-onset preeclampsia if left untreated. TNF superfamily cytokine, LIGHT has recently been reported to contribute to pathophysiology of preeclampsia. The present study aimed to investigate the involvement of LIGHT in h...

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Auteurs principaux: Takayuki Iriyama, Guan Wang, Midori Yoshikawa, Nobuko Mimura, Haruka Matsui, Seisuke Sayama, Keiichi Kumasawa, Takeshi Nagamatsu, Kaori Koga, Tomomi Kotani, Kaoru Niimi, Eiko Yamamoto, Rodney E. Kellems, Yang Xia, Yutaka Osuga, Tomoyuki Fujii
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/aaab15f46b934577b2c4637a70f86b06
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https://doaj.org/article/aaab15f46b934577b2c4637a70f86b06

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