Charged residues distribution modulates selectivity of the open state of human isoforms of the voltage dependent anion-selective channel.

Charged residues distribution modulates selectivity of the open state of human isoforms of the voltage dependent anion-selective channel.

Voltage Dependent Anion-selective Channels (VDACs) are pore-forming proteins located in the outer mitochondrial membrane. They are responsible for the access of ions and energetic metabolites into the inner membrane transport systems. Three VDAC isoforms exist in mammalian, but their specific role i...

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Autores principales: Giuseppe Federico Amodeo, Mariano Andrea Scorciapino, Angela Messina, Vito De Pinto, Matteo Ceccarelli
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/aaad390f03454faf80df6ff946c64f56
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