Wilm’s tumor 1 promotes memory flexibility
Impairments in memory flexibility are associated with neuropsychiatric disorders such as PTSD and autism. Here, the authors report that the transcriptional repressor Wilm's Tumor 1 regulates synaptic plasticity leading to weakening of memory strength and enabling memory flexibility.
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Nature Portfolio
2019
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| Acceso en línea: | https://doaj.org/article/aaada62663944bd6bb6bd2a1e13d925c |
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oai:doaj.org-article:aaada62663944bd6bb6bd2a1e13d925c2021-12-02T15:36:19ZWilm’s tumor 1 promotes memory flexibility10.1038/s41467-019-11781-x2041-1723https://doaj.org/article/aaada62663944bd6bb6bd2a1e13d925c2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11781-xhttps://doaj.org/toc/2041-1723Impairments in memory flexibility are associated with neuropsychiatric disorders such as PTSD and autism. Here, the authors report that the transcriptional repressor Wilm's Tumor 1 regulates synaptic plasticity leading to weakening of memory strength and enabling memory flexibility.Chiara MariottiniLeonardo MunariEllen GunzelJoseph M. SecoNikos TzavarasJens HansenSarah A. SternVirginia GaoHossein AleyasinAli SharmaEvren U. AzelogluGeorgia E. HodesScott J. RussoVicki HuffMarc R. BirtwistleRobert D. BlitzerCristina M. AlberiniRavi IyengarNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Chiara Mariottini Leonardo Munari Ellen Gunzel Joseph M. Seco Nikos Tzavaras Jens Hansen Sarah A. Stern Virginia Gao Hossein Aleyasin Ali Sharma Evren U. Azeloglu Georgia E. Hodes Scott J. Russo Vicki Huff Marc R. Birtwistle Robert D. Blitzer Cristina M. Alberini Ravi Iyengar Wilm’s tumor 1 promotes memory flexibility |
| description |
Impairments in memory flexibility are associated with neuropsychiatric disorders such as PTSD and autism. Here, the authors report that the transcriptional repressor Wilm's Tumor 1 regulates synaptic plasticity leading to weakening of memory strength and enabling memory flexibility. |
| format |
article |
| author |
Chiara Mariottini Leonardo Munari Ellen Gunzel Joseph M. Seco Nikos Tzavaras Jens Hansen Sarah A. Stern Virginia Gao Hossein Aleyasin Ali Sharma Evren U. Azeloglu Georgia E. Hodes Scott J. Russo Vicki Huff Marc R. Birtwistle Robert D. Blitzer Cristina M. Alberini Ravi Iyengar |
| author_facet |
Chiara Mariottini Leonardo Munari Ellen Gunzel Joseph M. Seco Nikos Tzavaras Jens Hansen Sarah A. Stern Virginia Gao Hossein Aleyasin Ali Sharma Evren U. Azeloglu Georgia E. Hodes Scott J. Russo Vicki Huff Marc R. Birtwistle Robert D. Blitzer Cristina M. Alberini Ravi Iyengar |
| author_sort |
Chiara Mariottini |
| title |
Wilm’s tumor 1 promotes memory flexibility |
| title_short |
Wilm’s tumor 1 promotes memory flexibility |
| title_full |
Wilm’s tumor 1 promotes memory flexibility |
| title_fullStr |
Wilm’s tumor 1 promotes memory flexibility |
| title_full_unstemmed |
Wilm’s tumor 1 promotes memory flexibility |
| title_sort |
wilm’s tumor 1 promotes memory flexibility |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/aaada62663944bd6bb6bd2a1e13d925c |
| work_keys_str_mv |
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