Targeting of intracellular Ca2+ stores as a therapeutic strategy against age-related neurotoxicities

Abstract Calcium dysregulation often underlies pathologies associated with aging and age-associated neurodegenerative diseases. Cells express a unique pattern of Ca2+ channels and pumps geared to fulfill specific physiological requirements and there is a decline in the fidelity of these processes wi...

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Autores principales: Joshua Goldberg, Antonio Currais, Gamze Ates, Ling Huang, Maxim Shokhirev, Pamela Maher, David Schubert
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/aab8f71534334401ab0fe2d1f969c108
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