Keratoprostheses for corneal blindness: a review of contemporary devices

Venkata S Avadhanam,1,2 Helen E Smith,2 Christopher Liu1–3 1Sussex Eye Hospital, 2Brighton and Sussex Medical School, Brighton, 3Tongdean Eye Clinic, Hove, UK Abstract: According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal t...

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Autores principales:	Avadhanam VS, Smith HE, Liu C
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/aac0d784f58b493d925814c43bcc9c23
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spelling	oai:doaj.org-article:aac0d784f58b493d925814c43bcc9c232021-12-02T02:46:26ZKeratoprostheses for corneal blindness: a review of contemporary devices1177-5483https://doaj.org/article/aac0d784f58b493d925814c43bcc9c232015-04-01T00:00:00Zhttp://www.dovepress.com/keratoprostheses-for-corneal-blindness-a-review-of-contemporary-device-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Venkata S Avadhanam,1,2 Helen E Smith,2 Christopher Liu1–3 1Sussex Eye Hospital, 2Brighton and Sussex Medical School, Brighton, 3Tongdean Eye Clinic, Hove, UK Abstract: According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases that produce corneal neovascularization, dry ocular surface and recurrent inflammation, or infections. A keratoprosthesis or KPro is the only alternative to restore vision when corneal graft is a doomed failure. Although a number of KPros have been proposed, only two devices, Boston type-1 KPro and osteo-odonto-KPro, have came to the fore. The former is totally synthetic and the latter is semi-biological in constitution. These two KPros have different surgical techniques and indications. Keratoprosthetic surgery is complex and should only be undertaken in specialized centers, where expertise, multidisciplinary teams, and resources are available. In this article, we briefly discuss some of the prominent historical KPros and contemporary devices. Keywords: keratoprosthesis, OOKP, KPro, Boston KPro, cornea, ocular surface Avadhanam VSSmith HELiu CDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 697-720 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Avadhanam VS Smith HE Liu C Keratoprostheses for corneal blindness: a review of contemporary devices
description	Venkata S Avadhanam,1,2 Helen E Smith,2 Christopher Liu1–3 1Sussex Eye Hospital, 2Brighton and Sussex Medical School, Brighton, 3Tongdean Eye Clinic, Hove, UK Abstract: According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases that produce corneal neovascularization, dry ocular surface and recurrent inflammation, or infections. A keratoprosthesis or KPro is the only alternative to restore vision when corneal graft is a doomed failure. Although a number of KPros have been proposed, only two devices, Boston type-1 KPro and osteo-odonto-KPro, have came to the fore. The former is totally synthetic and the latter is semi-biological in constitution. These two KPros have different surgical techniques and indications. Keratoprosthetic surgery is complex and should only be undertaken in specialized centers, where expertise, multidisciplinary teams, and resources are available. In this article, we briefly discuss some of the prominent historical KPros and contemporary devices. Keywords: keratoprosthesis, OOKP, KPro, Boston KPro, cornea, ocular surface
format	article
author	Avadhanam VS Smith HE Liu C
author_facet	Avadhanam VS Smith HE Liu C
author_sort	Avadhanam VS
title	Keratoprostheses for corneal blindness: a review of contemporary devices
title_short	Keratoprostheses for corneal blindness: a review of contemporary devices
title_full	Keratoprostheses for corneal blindness: a review of contemporary devices
title_fullStr	Keratoprostheses for corneal blindness: a review of contemporary devices
title_full_unstemmed	Keratoprostheses for corneal blindness: a review of contemporary devices
title_sort	keratoprostheses for corneal blindness: a review of contemporary devices
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/aac0d784f58b493d925814c43bcc9c23
work_keys_str_mv	AT avadhanamvs keratoprosthesesforcornealblindnessareviewofcontemporarydevices AT smithhe keratoprosthesesforcornealblindnessareviewofcontemporarydevices AT liuc keratoprosthesesforcornealblindnessareviewofcontemporarydevices
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Keratoprostheses for corneal blindness: a review of contemporary devices

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