Subanesthetic ketamine rapidly alters medial prefrontal miRNAs involved in ubiquitin-mediated proteolysis.

Ketamine is a dissociative anesthetic and a non-competitive NMDAR antagonist. At subanesthetic dose, ketamine can relieve pain and work as a fast-acting antidepressant, but the underlying molecular mechanism remains elusive. This study aimed to investigate the mode of action underlying the effects o...

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Autores principales: Yunjung Choi, Baeksun Kim, Suji Ham, Sooyoung Chung, Sungho Maeng, Hye-Sun Kim, Heh-In Im
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/aad8d89e18614e7ba6b6ef07dc77fd95
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