Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction

Cognitive behaviours are encoded and regulated by coordinated activity-induced transcriptional changes. Through single-cell RNA sequencing, the authors classify diverse cell types in mouse prefrontal cortex and analyze their transcriptional adaptations in adolescence and drug addiction.

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Detalles Bibliográficos
Autores principales: Aritra Bhattacherjee, Mohamed Nadhir Djekidel, Renchao Chen, Wenqiang Chen, Luis M. Tuesta, Yi Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/aad9d39ab4684044881d90f446251d86
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Sumario:Cognitive behaviours are encoded and regulated by coordinated activity-induced transcriptional changes. Through single-cell RNA sequencing, the authors classify diverse cell types in mouse prefrontal cortex and analyze their transcriptional adaptations in adolescence and drug addiction.