Danazol mediates collateral sensitivity via STAT3/Myc related pathway in multidrug-resistant cancer cells

Danazol mediates collateral sensitivity via STAT3/Myc related pathway in multidrug-resistant cancer cells

Abstract Multidrug resistance presents an obstacle in cancer treatment. Among numerous combative strategies, collateral sensitivity (CS) drugs have opened a new avenue to defeat cancer by exploiting selective toxicity against multidrug-resistant (MDR) cancer. In the present study, a clinically used...

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Autores principales: Ying-Tzu Chang, Yu-Ning Teng, Kun-I Lin, Charles C. N. Wang, Susan L. Morris-Natschke, Kuo-Hsiung Lee, Chin-Chuan Hung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/aadb4fb6502e4754853b555fcbdbf894
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