Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor

Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor

Monitoring DNA binding and single-base mismatches accurately in real time is difficult, especially for miniaturized devices. Here the authors report a graphene field-effect transistor array capable of reliably measuring DNA hybridization kinetics and affinity at the picomolar level.

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Detalles Bibliográficos
Autores principales: Shicai Xu, Jian Zhan, Baoyuan Man, Shouzhen Jiang, Weiwei Yue, Shoubao Gao, Chengang Guo, Hanping Liu, Zhenhua Li, Jihua Wang, Yaoqi Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/aae2dd43934f415a82bf00c21e1a2521
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