Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development

The tools for constructing cell lineages from single cell data are limited. Here, the authors present Mpath: an algorithm to derive multi-branching trajectories using neighbourhood-based cell state transitions, and use this to predict developmental trajectories in dendritic and muscle cells.

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Autores principales:	Jinmiao Chen, Andreas Schlitzer, Svetoslav Chakarov, Florent Ginhoux, Michael Poidinger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aae42a9a97c4479cb291f76d450c86e4
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spelling	oai:doaj.org-article:aae42a9a97c4479cb291f76d450c86e42021-12-02T15:35:24ZMpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development10.1038/ncomms119882041-1723https://doaj.org/article/aae42a9a97c4479cb291f76d450c86e42016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11988https://doaj.org/toc/2041-1723The tools for constructing cell lineages from single cell data are limited. Here, the authors present Mpath: an algorithm to derive multi-branching trajectories using neighbourhood-based cell state transitions, and use this to predict developmental trajectories in dendritic and muscle cells.Jinmiao ChenAndreas SchlitzerSvetoslav ChakarovFlorent GinhouxMichael PoidingerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jinmiao Chen Andreas Schlitzer Svetoslav Chakarov Florent Ginhoux Michael Poidinger Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development
description	The tools for constructing cell lineages from single cell data are limited. Here, the authors present Mpath: an algorithm to derive multi-branching trajectories using neighbourhood-based cell state transitions, and use this to predict developmental trajectories in dendritic and muscle cells.
format	article
author	Jinmiao Chen Andreas Schlitzer Svetoslav Chakarov Florent Ginhoux Michael Poidinger
author_facet	Jinmiao Chen Andreas Schlitzer Svetoslav Chakarov Florent Ginhoux Michael Poidinger
author_sort	Jinmiao Chen
title	Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development
title_short	Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development
title_full	Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development
title_fullStr	Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development
title_full_unstemmed	Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development
title_sort	mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/aae42a9a97c4479cb291f76d450c86e4
work_keys_str_mv	AT jinmiaochen mpathmapsmultibranchingsinglecelltrajectoriesrevealingprogenitorcellprogressionduringdevelopment AT andreasschlitzer mpathmapsmultibranchingsinglecelltrajectoriesrevealingprogenitorcellprogressionduringdevelopment AT svetoslavchakarov mpathmapsmultibranchingsinglecelltrajectoriesrevealingprogenitorcellprogressionduringdevelopment AT florentginhoux mpathmapsmultibranchingsinglecelltrajectoriesrevealingprogenitorcellprogressionduringdevelopment AT michaelpoidinger mpathmapsmultibranchingsinglecelltrajectoriesrevealingprogenitorcellprogressionduringdevelopment
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Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development

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