Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development
The tools for constructing cell lineages from single cell data are limited. Here, the authors present Mpath: an algorithm to derive multi-branching trajectories using neighbourhood-based cell state transitions, and use this to predict developmental trajectories in dendritic and muscle cells.
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Main Authors: | Jinmiao Chen, Andreas Schlitzer, Svetoslav Chakarov, Florent Ginhoux, Michael Poidinger |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Subjects: | |
Online Access: | https://doaj.org/article/aae42a9a97c4479cb291f76d450c86e4 |
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