The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells

Ito et al. generated and characterized multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells (TIL-iPSC) using human colorectal cancer specimens. They demonstrated that the newly-generated T cells retained intrinsic characters and acquired improved functions wit...

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Autores principales:	Takeshi Ito, Yohei Kawai, Yutaka Yasui, Shoichi Iriguchi, Atsutaka Minagawa, Tomoko Ishii, Hiroyuki Miyoshi, M. Mark Taketo, Kenji Kawada, Kazutaka Obama, Yoshiharu Sakai, Shin Kaneko
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/aae603ed56fd496c983a89c36cc8f3f1
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spelling	oai:doaj.org-article:aae603ed56fd496c983a89c36cc8f3f12021-12-02T14:59:29ZThe therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells10.1038/s42003-021-02195-x2399-3642https://doaj.org/article/aae603ed56fd496c983a89c36cc8f3f12021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02195-xhttps://doaj.org/toc/2399-3642Ito et al. generated and characterized multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells (TIL-iPSC) using human colorectal cancer specimens. They demonstrated that the newly-generated T cells retained intrinsic characters and acquired improved functions with less differentiated profiles, thus constituting a potential therapeutic anti-cancer tool.Takeshi ItoYohei KawaiYutaka YasuiShoichi IriguchiAtsutaka MinagawaTomoko IshiiHiroyuki MiyoshiM. Mark TaketoKenji KawadaKazutaka ObamaYoshiharu SakaiShin KanekoNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Takeshi Ito Yohei Kawai Yutaka Yasui Shoichi Iriguchi Atsutaka Minagawa Tomoko Ishii Hiroyuki Miyoshi M. Mark Taketo Kenji Kawada Kazutaka Obama Yoshiharu Sakai Shin Kaneko The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells
description	Ito et al. generated and characterized multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells (TIL-iPSC) using human colorectal cancer specimens. They demonstrated that the newly-generated T cells retained intrinsic characters and acquired improved functions with less differentiated profiles, thus constituting a potential therapeutic anti-cancer tool.
format	article
author	Takeshi Ito Yohei Kawai Yutaka Yasui Shoichi Iriguchi Atsutaka Minagawa Tomoko Ishii Hiroyuki Miyoshi M. Mark Taketo Kenji Kawada Kazutaka Obama Yoshiharu Sakai Shin Kaneko
author_facet	Takeshi Ito Yohei Kawai Yutaka Yasui Shoichi Iriguchi Atsutaka Minagawa Tomoko Ishii Hiroyuki Miyoshi M. Mark Taketo Kenji Kawada Kazutaka Obama Yoshiharu Sakai Shin Kaneko
author_sort	Takeshi Ito
title	The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells
title_short	The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells
title_full	The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells
title_fullStr	The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells
title_full_unstemmed	The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells
title_sort	therapeutic potential of multiclonal tumoricidal t cells derived from tumor infiltrating lymphocyte-1derived ips cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/aae603ed56fd496c983a89c36cc8f3f1
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The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells

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