Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture

By encapsulating proteins in giant unilamellar vesicles, Bashirzadeh et al find that actin crosslinkers, α-actinin and fascin, can self-assemble with actin into complex structures that depend on the degree of confinement. Further analysis and modeling show that α-actinin and fascin sort to separate...

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Autores principales: Yashar Bashirzadeh, Steven A. Redford, Chatipat Lorpaiboon, Alessandro Groaz, Hossein Moghimianavval, Thomas Litschel, Petra Schwille, Glen M. Hocky, Aaron R. Dinner, Allen P. Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/aaed8fb477af48c18e68c17570b33fa1
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