Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture
By encapsulating proteins in giant unilamellar vesicles, Bashirzadeh et al find that actin crosslinkers, α-actinin and fascin, can self-assemble with actin into complex structures that depend on the degree of confinement. Further analysis and modeling show that α-actinin and fascin sort to separate...
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Main Authors: | Yashar Bashirzadeh, Steven A. Redford, Chatipat Lorpaiboon, Alessandro Groaz, Hossein Moghimianavval, Thomas Litschel, Petra Schwille, Glen M. Hocky, Aaron R. Dinner, Allen P. Liu |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/aaed8fb477af48c18e68c17570b33fa1 |
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