Network enhancement as a general method to denoise weighted biological networks

Technical noise in experiments is unavoidable, but it introduces inaccuracies into the biological networks we infer from the data. Here, the authors introduce a diffusion-based method for denoising undirected, weighted networks, and show that it improves the performances of downstream analyses.

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Autores principales:	Bo Wang, Armin Pourshafeie, Marinka Zitnik, Junjie Zhu, Carlos D. Bustamante, Serafim Batzoglou, Jure Leskovec
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aaf42c026bf24c03abbdc755b39fedc1
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id	oai:doaj.org-article:aaf42c026bf24c03abbdc755b39fedc1
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spelling	oai:doaj.org-article:aaf42c026bf24c03abbdc755b39fedc12021-12-02T16:50:11ZNetwork enhancement as a general method to denoise weighted biological networks10.1038/s41467-018-05469-x2041-1723https://doaj.org/article/aaf42c026bf24c03abbdc755b39fedc12018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05469-xhttps://doaj.org/toc/2041-1723Technical noise in experiments is unavoidable, but it introduces inaccuracies into the biological networks we infer from the data. Here, the authors introduce a diffusion-based method for denoising undirected, weighted networks, and show that it improves the performances of downstream analyses.Bo WangArmin PourshafeieMarinka ZitnikJunjie ZhuCarlos D. BustamanteSerafim BatzoglouJure LeskovecNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bo Wang Armin Pourshafeie Marinka Zitnik Junjie Zhu Carlos D. Bustamante Serafim Batzoglou Jure Leskovec Network enhancement as a general method to denoise weighted biological networks
description	Technical noise in experiments is unavoidable, but it introduces inaccuracies into the biological networks we infer from the data. Here, the authors introduce a diffusion-based method for denoising undirected, weighted networks, and show that it improves the performances of downstream analyses.
format	article
author	Bo Wang Armin Pourshafeie Marinka Zitnik Junjie Zhu Carlos D. Bustamante Serafim Batzoglou Jure Leskovec
author_facet	Bo Wang Armin Pourshafeie Marinka Zitnik Junjie Zhu Carlos D. Bustamante Serafim Batzoglou Jure Leskovec
author_sort	Bo Wang
title	Network enhancement as a general method to denoise weighted biological networks
title_short	Network enhancement as a general method to denoise weighted biological networks
title_full	Network enhancement as a general method to denoise weighted biological networks
title_fullStr	Network enhancement as a general method to denoise weighted biological networks
title_full_unstemmed	Network enhancement as a general method to denoise weighted biological networks
title_sort	network enhancement as a general method to denoise weighted biological networks
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/aaf42c026bf24c03abbdc755b39fedc1
work_keys_str_mv	AT bowang networkenhancementasageneralmethodtodenoiseweightedbiologicalnetworks AT arminpourshafeie networkenhancementasageneralmethodtodenoiseweightedbiologicalnetworks AT marinkazitnik networkenhancementasageneralmethodtodenoiseweightedbiologicalnetworks AT junjiezhu networkenhancementasageneralmethodtodenoiseweightedbiologicalnetworks AT carlosdbustamante networkenhancementasageneralmethodtodenoiseweightedbiologicalnetworks AT serafimbatzoglou networkenhancementasageneralmethodtodenoiseweightedbiologicalnetworks AT jureleskovec networkenhancementasageneralmethodtodenoiseweightedbiologicalnetworks
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Network enhancement as a general method to denoise weighted biological networks

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