Connective tissue disease: an important cause of reoperation of aorta

Objective To investigate the clinical characteristics and surgical treatment experience of reoperation of aorta caused by connective tissue disease. Methods The perioperative and follow-up data of 45 patients with reoperation of aorta in our department from January 2010 to December 2019 were collect...

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Autores principales:	LI Tianbo, LIU Chencheng, XU Bo, WANG Yong, XIAO Yingbin
Formato:	article
Lenguaje:	ZH
Publicado:	Editorial Office of Journal of Third Military Medical University 2021
Materias:	cardiovascular surgery reoperation of aorta connective tissue disease behcet's disease Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/aaf92fa7ad06492f89099294ba855a57
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spelling	oai:doaj.org-article:aaf92fa7ad06492f89099294ba855a572021-11-28T10:53:08ZConnective tissue disease: an important cause of reoperation of aorta10.16016/j.1000-5404.2021051531000-5404https://doaj.org/article/aaf92fa7ad06492f89099294ba855a572021-11-01T00:00:00Zhttp://aammt.tmmu.edu.cn/Upload/rhtml/202105153.htmhttps://doaj.org/toc/1000-5404Objective To investigate the clinical characteristics and surgical treatment experience of reoperation of aorta caused by connective tissue disease. Methods The perioperative and follow-up data of 45 patients with reoperation of aorta in our department from January 2010 to December 2019 were collected and retrospectively analyzed. They were 33 males and 12 females, at an age from 9~73 (46.0±14.1) years. There were 19 cases of connective tissue disease, including 9 cases of Behcet's disease, 4 cases of Marfan's syndrome and 6 cases of bicuspid aortic valve. Bentall operation was performed in 24 cases, Bentall+total aortic arch replacement+descending aortic stent elephant trunk operation in 6 cases, Bentall+mitral valve replacement in 5 cases, and other types of operation in 10 cases. All the patients were followed up for 17~113 (58.5±25.6) months. Results Reoperation of aorta was quite rare, only accounting for 7.3% of reoperation of cardiovascular surgeries in our department (45/617), while connective tissue disease took 42.2% (19/45) among the reoperation. There were 5 patients who died during perioperative period, including 2 cases due to cardiac arrest, 2 cases to persistent low cardiac output syndrome and 1 case to refractory hypoxemia. During the follow-up, 7 cases died, including 4 cases due to Behcet's disease, 1 case to Marfan's syndrome and 2 cases to aortic dissection. The outcomes of other cases were satisfactory. Kaplan-Meier survival analysis indicated the mortality rate of Behect's disease was the highest during follow-up period (Log rank test, P=0.0082). Conclusion Connective tissue disease is an important cause of aortic reoperation. Behcet's disease has the highest mortality and the worst prognosis.LI TianboLIU ChenchengXU BoWANG YongXIAO YingbinEditorial Office of Journal of Third Military Medical Universityarticlecardiovascular surgeryreoperation of aortaconnective tissue diseasebehcet's diseaseMedicine (General)R5-920ZHDi-san junyi daxue xuebao, Vol 43, Iss 22, Pp 2449-2454 (2021)
institution	DOAJ
collection	DOAJ
language	ZH
topic	cardiovascular surgery reoperation of aorta connective tissue disease behcet's disease Medicine (General) R5-920
spellingShingle	cardiovascular surgery reoperation of aorta connective tissue disease behcet's disease Medicine (General) R5-920 LI Tianbo LIU Chencheng XU Bo WANG Yong XIAO Yingbin Connective tissue disease: an important cause of reoperation of aorta
description	Objective To investigate the clinical characteristics and surgical treatment experience of reoperation of aorta caused by connective tissue disease. Methods The perioperative and follow-up data of 45 patients with reoperation of aorta in our department from January 2010 to December 2019 were collected and retrospectively analyzed. They were 33 males and 12 females, at an age from 9~73 (46.0±14.1) years. There were 19 cases of connective tissue disease, including 9 cases of Behcet's disease, 4 cases of Marfan's syndrome and 6 cases of bicuspid aortic valve. Bentall operation was performed in 24 cases, Bentall+total aortic arch replacement+descending aortic stent elephant trunk operation in 6 cases, Bentall+mitral valve replacement in 5 cases, and other types of operation in 10 cases. All the patients were followed up for 17~113 (58.5±25.6) months. Results Reoperation of aorta was quite rare, only accounting for 7.3% of reoperation of cardiovascular surgeries in our department (45/617), while connective tissue disease took 42.2% (19/45) among the reoperation. There were 5 patients who died during perioperative period, including 2 cases due to cardiac arrest, 2 cases to persistent low cardiac output syndrome and 1 case to refractory hypoxemia. During the follow-up, 7 cases died, including 4 cases due to Behcet's disease, 1 case to Marfan's syndrome and 2 cases to aortic dissection. The outcomes of other cases were satisfactory. Kaplan-Meier survival analysis indicated the mortality rate of Behect's disease was the highest during follow-up period (Log rank test, P=0.0082). Conclusion Connective tissue disease is an important cause of aortic reoperation. Behcet's disease has the highest mortality and the worst prognosis.
format	article
author	LI Tianbo LIU Chencheng XU Bo WANG Yong XIAO Yingbin
author_facet	LI Tianbo LIU Chencheng XU Bo WANG Yong XIAO Yingbin
author_sort	LI Tianbo
title	Connective tissue disease: an important cause of reoperation of aorta
title_short	Connective tissue disease: an important cause of reoperation of aorta
title_full	Connective tissue disease: an important cause of reoperation of aorta
title_fullStr	Connective tissue disease: an important cause of reoperation of aorta
title_full_unstemmed	Connective tissue disease: an important cause of reoperation of aorta
title_sort	connective tissue disease: an important cause of reoperation of aorta
publisher	Editorial Office of Journal of Third Military Medical University
publishDate	2021
url	https://doaj.org/article/aaf92fa7ad06492f89099294ba855a57
work_keys_str_mv	AT litianbo connectivetissuediseaseanimportantcauseofreoperationofaorta AT liuchencheng connectivetissuediseaseanimportantcauseofreoperationofaorta AT xubo connectivetissuediseaseanimportantcauseofreoperationofaorta AT wangyong connectivetissuediseaseanimportantcauseofreoperationofaorta AT xiaoyingbin connectivetissuediseaseanimportantcauseofreoperationofaorta
_version_	1718408277419622400

Connective tissue disease: an important cause of reoperation of aorta

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