BMP-7 does not protect against bleomycin-induced lung or skin fibrosis.
Bone morphogenic protein (BMP)-7 is a member of the BMP family which are structurally and functionally related, and part of the TGFbeta super family of growth factors. BMP-7 has been reported to inhibit renal fibrosis and TGFbeta1-induced epithelial-mesenchymal transition (EMT), in part through nega...
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Autores principales: | Lynne A Murray, Tillie L Hackett, Stephanie M Warner, Furquan Shaheen, Rochelle L Argentieri, Paul Dudas, Francis X Farrell, Darryl A Knight |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2008
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Materias: | |
Acceso en línea: | https://doaj.org/article/aaff4464c87b4da18f8a904246b05236 |
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