A Targetron-Recombinase System for Large-Scale Genome Engineering of Clostridia

ABSTRACT Clostridia are a group of Gram-positive anaerobic bacteria of medical and industrial importance for which limited genetic methods are available. Here, we demonstrate an approach to make large genomic deletions and insertions in the model Clostridium phytofermentans by combining designed gro...

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Autores principales: Tristan Cerisy, William Rostain, Audam Chhun, Magali Boutard, Marcel Salanoubat, Andrew C. Tolonen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/ab05c80fb10a4397b257fe22ee7054a1
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