A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers
Breast cancer is separated into multiple subtypes based on the expression of HER2 and hormone receptors. Here, the authors report the whole genome sequence of 64 HER2 positive tumours and show that these can be further separated into four groups with different gene expression profiles and genomic fe...
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Nature Portfolio
2016
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oai:doaj.org-article:ab0d2ca4b11b4f8888dd3d70ad443efe2021-12-02T16:49:26ZA whole-genome sequence and transcriptome perspective on HER2-positive breast cancers10.1038/ncomms122222041-1723https://doaj.org/article/ab0d2ca4b11b4f8888dd3d70ad443efe2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12222https://doaj.org/toc/2041-1723Breast cancer is separated into multiple subtypes based on the expression of HER2 and hormone receptors. Here, the authors report the whole genome sequence of 64 HER2 positive tumours and show that these can be further separated into four groups with different gene expression profiles and genomic features.Anthony FerrariAnne Vincent-SalomonXavier PivotAnne-Sophie SertierEmilie ThomasLaurie TononSandrine BoyaultEskeatnaf MulugetaIsabelle TreilleuxGaëtan MacGroganLaurent ArnouldJanice KielbassaVincent Le TexierHélène BlanchéJean-François DeleuzeJocelyne JacquemierMarie-Christine MathieuFrédérique Penault-LlorcaFrédéric BibeauOdette MarianiCécile ManninaJean-Yves PiergaOlivier TrédanThomas BachelotHervé BonnefoiGilles RomieuPierre FumoleauSuzette DelalogeMaria RiosJean-Marc FerreroCarole TarpinCatherine BouteilleFabien CalvoIvo Glynne GutMarta GutSancha MartinSerena Nik-ZainalMichael R. StrattonIris PauportéPierre SaintignyDaniel BirnbaumAlain ViariGilles ThomasNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
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| collection |
DOAJ |
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EN |
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Science Q Anthony Ferrari Anne Vincent-Salomon Xavier Pivot Anne-Sophie Sertier Emilie Thomas Laurie Tonon Sandrine Boyault Eskeatnaf Mulugeta Isabelle Treilleux Gaëtan MacGrogan Laurent Arnould Janice Kielbassa Vincent Le Texier Hélène Blanché Jean-François Deleuze Jocelyne Jacquemier Marie-Christine Mathieu Frédérique Penault-Llorca Frédéric Bibeau Odette Mariani Cécile Mannina Jean-Yves Pierga Olivier Trédan Thomas Bachelot Hervé Bonnefoi Gilles Romieu Pierre Fumoleau Suzette Delaloge Maria Rios Jean-Marc Ferrero Carole Tarpin Catherine Bouteille Fabien Calvo Ivo Glynne Gut Marta Gut Sancha Martin Serena Nik-Zainal Michael R. Stratton Iris Pauporté Pierre Saintigny Daniel Birnbaum Alain Viari Gilles Thomas A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers |
| description |
Breast cancer is separated into multiple subtypes based on the expression of HER2 and hormone receptors. Here, the authors report the whole genome sequence of 64 HER2 positive tumours and show that these can be further separated into four groups with different gene expression profiles and genomic features. |
| format |
article |
| author |
Anthony Ferrari Anne Vincent-Salomon Xavier Pivot Anne-Sophie Sertier Emilie Thomas Laurie Tonon Sandrine Boyault Eskeatnaf Mulugeta Isabelle Treilleux Gaëtan MacGrogan Laurent Arnould Janice Kielbassa Vincent Le Texier Hélène Blanché Jean-François Deleuze Jocelyne Jacquemier Marie-Christine Mathieu Frédérique Penault-Llorca Frédéric Bibeau Odette Mariani Cécile Mannina Jean-Yves Pierga Olivier Trédan Thomas Bachelot Hervé Bonnefoi Gilles Romieu Pierre Fumoleau Suzette Delaloge Maria Rios Jean-Marc Ferrero Carole Tarpin Catherine Bouteille Fabien Calvo Ivo Glynne Gut Marta Gut Sancha Martin Serena Nik-Zainal Michael R. Stratton Iris Pauporté Pierre Saintigny Daniel Birnbaum Alain Viari Gilles Thomas |
| author_facet |
Anthony Ferrari Anne Vincent-Salomon Xavier Pivot Anne-Sophie Sertier Emilie Thomas Laurie Tonon Sandrine Boyault Eskeatnaf Mulugeta Isabelle Treilleux Gaëtan MacGrogan Laurent Arnould Janice Kielbassa Vincent Le Texier Hélène Blanché Jean-François Deleuze Jocelyne Jacquemier Marie-Christine Mathieu Frédérique Penault-Llorca Frédéric Bibeau Odette Mariani Cécile Mannina Jean-Yves Pierga Olivier Trédan Thomas Bachelot Hervé Bonnefoi Gilles Romieu Pierre Fumoleau Suzette Delaloge Maria Rios Jean-Marc Ferrero Carole Tarpin Catherine Bouteille Fabien Calvo Ivo Glynne Gut Marta Gut Sancha Martin Serena Nik-Zainal Michael R. Stratton Iris Pauporté Pierre Saintigny Daniel Birnbaum Alain Viari Gilles Thomas |
| author_sort |
Anthony Ferrari |
| title |
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers |
| title_short |
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers |
| title_full |
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers |
| title_fullStr |
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers |
| title_full_unstemmed |
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers |
| title_sort |
whole-genome sequence and transcriptome perspective on her2-positive breast cancers |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/ab0d2ca4b11b4f8888dd3d70ad443efe |
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