Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography

Jun Liu, Qiang Liu, Hua Yu, Ye Xia, Hui Zhang, Chao Geng, Lihong Dong Department of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People’s Republic of ChinaCorrespondence: Lihong DongDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical Universit...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Liu J, Liu Q, Yu H, Xia Y, Zhang H, Geng C, Dong L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	cataracts phacoemulsification optical coherence tomography macular thickness microvascular density Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/ab1543d120cd41fc840fef9c57a46d4c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ab1543d120cd41fc840fef9c57a46d4c
record_format	dspace
spelling	oai:doaj.org-article:ab1543d120cd41fc840fef9c57a46d4c2021-12-02T16:50:25ZMicrovascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography1178-203Xhttps://doaj.org/article/ab1543d120cd41fc840fef9c57a46d4c2021-05-01T00:00:00Zhttps://www.dovepress.com/microvascular-changes-in-macular-area-after-phacoemulsification-and-it-peer-reviewed-fulltext-article-TCRMhttps://doaj.org/toc/1178-203XJun Liu, Qiang Liu, Hua Yu, Ye Xia, Hui Zhang, Chao Geng, Lihong Dong Department of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People’s Republic of ChinaCorrespondence: Lihong DongDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People’s Republic of ChinaTel +86-551-82324267Email dlhyp6583@sina.comObjective: To investigate macular vascular changes and underlying influencing factors using optical coherence tomography angiography (OCTA) after phacoemulsification in patients with cataracts.Methods: Patients diagnosed with cataracts at the First Affiliated Hospital of Anhui Medical University from March to September 2019 were included. The macular retinal thickness, the microvascular density in the foveal, parafoveal, and perifoveal area, and the area of the foveal avascular zone (FAZ) were measured using OCTA at baseline, 1-week, 1-month, and 3-month post-operation.Results: Forty-seven cataract patients (58 eyes) were eligible for this study. Compared with baseline thickness, the foveal, parafoveal, and perifoveal thicknesses, particularly in the inner retina, significantly increased at 1- and 3-month post-operation (P< 0.05). There was a nonsignificant difference in the microvascular density of the foveal and perifoveal areas at 1-week, 1-month, and 3-month post-operation (P> 0.05). At 1-month post-operation, the deep vessel density at the perifovea significantly increased (P< 0.05). The FAZ area significantly diminished at 1- and 3-month post-operation compared with the baseline data (P< 0.05).Conclusion: Phacoemulsification offers a satisfactory efficacy response, with an increased macular thickness, reduced FAZ area, and nonsignificant changes in the microvascular density at the perifovea after surgery.Keywords: cataracts, phacoemulsification, optical coherence tomography, macular thickness, microvascular densityLiu JLiu QYu HXia YZhang HGeng CDong LDove Medical Pressarticlecataractsphacoemulsificationoptical coherence tomographymacular thicknessmicrovascular densityTherapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 17, Pp 405-414 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cataracts phacoemulsification optical coherence tomography macular thickness microvascular density Therapeutics. Pharmacology RM1-950
spellingShingle	cataracts phacoemulsification optical coherence tomography macular thickness microvascular density Therapeutics. Pharmacology RM1-950 Liu J Liu Q Yu H Xia Y Zhang H Geng C Dong L Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography
description	Jun Liu, Qiang Liu, Hua Yu, Ye Xia, Hui Zhang, Chao Geng, Lihong Dong Department of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People’s Republic of ChinaCorrespondence: Lihong DongDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People’s Republic of ChinaTel +86-551-82324267Email dlhyp6583@sina.comObjective: To investigate macular vascular changes and underlying influencing factors using optical coherence tomography angiography (OCTA) after phacoemulsification in patients with cataracts.Methods: Patients diagnosed with cataracts at the First Affiliated Hospital of Anhui Medical University from March to September 2019 were included. The macular retinal thickness, the microvascular density in the foveal, parafoveal, and perifoveal area, and the area of the foveal avascular zone (FAZ) were measured using OCTA at baseline, 1-week, 1-month, and 3-month post-operation.Results: Forty-seven cataract patients (58 eyes) were eligible for this study. Compared with baseline thickness, the foveal, parafoveal, and perifoveal thicknesses, particularly in the inner retina, significantly increased at 1- and 3-month post-operation (P< 0.05). There was a nonsignificant difference in the microvascular density of the foveal and perifoveal areas at 1-week, 1-month, and 3-month post-operation (P> 0.05). At 1-month post-operation, the deep vessel density at the perifovea significantly increased (P< 0.05). The FAZ area significantly diminished at 1- and 3-month post-operation compared with the baseline data (P< 0.05).Conclusion: Phacoemulsification offers a satisfactory efficacy response, with an increased macular thickness, reduced FAZ area, and nonsignificant changes in the microvascular density at the perifovea after surgery.Keywords: cataracts, phacoemulsification, optical coherence tomography, macular thickness, microvascular density
format	article
author	Liu J Liu Q Yu H Xia Y Zhang H Geng C Dong L
author_facet	Liu J Liu Q Yu H Xia Y Zhang H Geng C Dong L
author_sort	Liu J
title	Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography
title_short	Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography
title_full	Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography
title_fullStr	Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography
title_full_unstemmed	Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography
title_sort	microvascular changes in macular area after phacoemulsification and its influencing factors assessed by optical coherence tomography angiography
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/ab1543d120cd41fc840fef9c57a46d4c
work_keys_str_mv	AT liuj microvascularchangesinmacularareaafterphacoemulsificationanditsinfluencingfactorsassessedbyopticalcoherencetomographyangiography AT liuq microvascularchangesinmacularareaafterphacoemulsificationanditsinfluencingfactorsassessedbyopticalcoherencetomographyangiography AT yuh microvascularchangesinmacularareaafterphacoemulsificationanditsinfluencingfactorsassessedbyopticalcoherencetomographyangiography AT xiay microvascularchangesinmacularareaafterphacoemulsificationanditsinfluencingfactorsassessedbyopticalcoherencetomographyangiography AT zhangh microvascularchangesinmacularareaafterphacoemulsificationanditsinfluencingfactorsassessedbyopticalcoherencetomographyangiography AT gengc microvascularchangesinmacularareaafterphacoemulsificationanditsinfluencingfactorsassessedbyopticalcoherencetomographyangiography AT dongl microvascularchangesinmacularareaafterphacoemulsificationanditsinfluencingfactorsassessedbyopticalcoherencetomographyangiography
_version_	1718383056776069120

Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography

Ejemplares similares