Cross-species oncogenic signatures of breast cancer in canine mammary tumors

Cross-species oncogenic signatures of breast cancer in canine mammary tumors

Comparison of spontaneous canine cancers and human cancers may illuminate future therapeutic avenues. Here, genomic analyses of these tumors highlights a convergence on PI3K-Akt oncogenic pathways.

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Main Authors: Tae-Min Kim, In Seok Yang, Byung-Joon Seung, Sejoon Lee, Dohyun Kim, Yoo-Jin Ha, Mi-kyoung Seo, Ka-Kyung Kim, Hyun Seok Kim, Jae-Ho Cheong, Jung-Hyang Sur, Hojung Nam, Sangwoo Kim
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
Q
Online Access:https://doaj.org/article/ab1a0a9b68044115ac3ec182334e71fc
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spelling oai:doaj.org-article:ab1a0a9b68044115ac3ec182334e71fc2021-12-02T17:01:30ZCross-species oncogenic signatures of breast cancer in canine mammary tumors10.1038/s41467-020-17458-02041-1723https://doaj.org/article/ab1a0a9b68044115ac3ec182334e71fc2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17458-0https://doaj.org/toc/2041-1723Comparison of spontaneous canine cancers and human cancers may illuminate future therapeutic avenues. Here, genomic analyses of these tumors highlights a convergence on PI3K-Akt oncogenic pathways.Tae-Min KimIn Seok YangByung-Joon SeungSejoon LeeDohyun KimYoo-Jin HaMi-kyoung SeoKa-Kyung KimHyun Seok KimJae-Ho CheongJung-Hyang SurHojung NamSangwoo KimNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tae-Min Kim
In Seok Yang
Byung-Joon Seung
Sejoon Lee
Dohyun Kim
Yoo-Jin Ha
Mi-kyoung Seo
Ka-Kyung Kim
Hyun Seok Kim
Jae-Ho Cheong
Jung-Hyang Sur
Hojung Nam
Sangwoo Kim
Cross-species oncogenic signatures of breast cancer in canine mammary tumors
description Comparison of spontaneous canine cancers and human cancers may illuminate future therapeutic avenues. Here, genomic analyses of these tumors highlights a convergence on PI3K-Akt oncogenic pathways.
format article
author Tae-Min Kim
In Seok Yang
Byung-Joon Seung
Sejoon Lee
Dohyun Kim
Yoo-Jin Ha
Mi-kyoung Seo
Ka-Kyung Kim
Hyun Seok Kim
Jae-Ho Cheong
Jung-Hyang Sur
Hojung Nam
Sangwoo Kim
author_facet Tae-Min Kim
In Seok Yang
Byung-Joon Seung
Sejoon Lee
Dohyun Kim
Yoo-Jin Ha
Mi-kyoung Seo
Ka-Kyung Kim
Hyun Seok Kim
Jae-Ho Cheong
Jung-Hyang Sur
Hojung Nam
Sangwoo Kim
author_sort Tae-Min Kim
title Cross-species oncogenic signatures of breast cancer in canine mammary tumors
title_short Cross-species oncogenic signatures of breast cancer in canine mammary tumors
title_full Cross-species oncogenic signatures of breast cancer in canine mammary tumors
title_fullStr Cross-species oncogenic signatures of breast cancer in canine mammary tumors
title_full_unstemmed Cross-species oncogenic signatures of breast cancer in canine mammary tumors
title_sort cross-species oncogenic signatures of breast cancer in canine mammary tumors
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ab1a0a9b68044115ac3ec182334e71fc
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AT inseokyang crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT byungjoonseung crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT sejoonlee crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT dohyunkim crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT yoojinha crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT mikyoungseo crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT kakyungkim crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT hyunseokkim crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT jaehocheong crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT junghyangsur crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT hojungnam crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
AT sangwookim crossspeciesoncogenicsignaturesofbreastcancerincaninemammarytumors
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