The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis
It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB polarity via FGF signallingin vitroand in zebrafish.
Guardado en:
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ab204da3ad6b440d8494627f04efac77 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:ab204da3ad6b440d8494627f04efac77 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:ab204da3ad6b440d8494627f04efac772021-12-02T14:40:47ZThe signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis10.1038/ncomms152792041-1723https://doaj.org/article/ab204da3ad6b440d8494627f04efac772017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15279https://doaj.org/toc/2041-1723It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB polarity via FGF signallingin vitroand in zebrafish.Qian GaoJunfeng ZhangXiumei WangYing LiuRongqiao HeXingfeng LiuFei WangJing FengDongling YangZhaoqing WangAnming MengXiyun YanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Qian Gao Junfeng Zhang Xiumei Wang Ying Liu Rongqiao He Xingfeng Liu Fei Wang Jing Feng Dongling Yang Zhaoqing Wang Anming Meng Xiyun Yan The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis |
description |
It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB polarity via FGF signallingin vitroand in zebrafish. |
format |
article |
author |
Qian Gao Junfeng Zhang Xiumei Wang Ying Liu Rongqiao He Xingfeng Liu Fei Wang Jing Feng Dongling Yang Zhaoqing Wang Anming Meng Xiyun Yan |
author_facet |
Qian Gao Junfeng Zhang Xiumei Wang Ying Liu Rongqiao He Xingfeng Liu Fei Wang Jing Feng Dongling Yang Zhaoqing Wang Anming Meng Xiyun Yan |
author_sort |
Qian Gao |
title |
The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis |
title_short |
The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis |
title_full |
The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis |
title_fullStr |
The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis |
title_full_unstemmed |
The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis |
title_sort |
signalling receptor mcam coordinates apical-basal polarity and planar cell polarity during morphogenesis |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/ab204da3ad6b440d8494627f04efac77 |
work_keys_str_mv |
AT qiangao thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT junfengzhang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT xiumeiwang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT yingliu thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT rongqiaohe thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT xingfengliu thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT feiwang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT jingfeng thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT donglingyang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT zhaoqingwang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT anmingmeng thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT xiyunyan thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT qiangao signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT junfengzhang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT xiumeiwang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT yingliu signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT rongqiaohe signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT xingfengliu signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT feiwang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT jingfeng signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT donglingyang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT zhaoqingwang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT anmingmeng signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis AT xiyunyan signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis |
_version_ |
1718390191302901760 |