The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis

It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB polarity via FGF signallingin vitroand in zebrafish.

Guardado en:
Detalles Bibliográficos
Autores principales: Qian Gao, Junfeng Zhang, Xiumei Wang, Ying Liu, Rongqiao He, Xingfeng Liu, Fei Wang, Jing Feng, Dongling Yang, Zhaoqing Wang, Anming Meng, Xiyun Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/ab204da3ad6b440d8494627f04efac77
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:ab204da3ad6b440d8494627f04efac77
record_format dspace
spelling oai:doaj.org-article:ab204da3ad6b440d8494627f04efac772021-12-02T14:40:47ZThe signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis10.1038/ncomms152792041-1723https://doaj.org/article/ab204da3ad6b440d8494627f04efac772017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15279https://doaj.org/toc/2041-1723It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB polarity via FGF signallingin vitroand in zebrafish.Qian GaoJunfeng ZhangXiumei WangYing LiuRongqiao HeXingfeng LiuFei WangJing FengDongling YangZhaoqing WangAnming MengXiyun YanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qian Gao
Junfeng Zhang
Xiumei Wang
Ying Liu
Rongqiao He
Xingfeng Liu
Fei Wang
Jing Feng
Dongling Yang
Zhaoqing Wang
Anming Meng
Xiyun Yan
The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis
description It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB polarity via FGF signallingin vitroand in zebrafish.
format article
author Qian Gao
Junfeng Zhang
Xiumei Wang
Ying Liu
Rongqiao He
Xingfeng Liu
Fei Wang
Jing Feng
Dongling Yang
Zhaoqing Wang
Anming Meng
Xiyun Yan
author_facet Qian Gao
Junfeng Zhang
Xiumei Wang
Ying Liu
Rongqiao He
Xingfeng Liu
Fei Wang
Jing Feng
Dongling Yang
Zhaoqing Wang
Anming Meng
Xiyun Yan
author_sort Qian Gao
title The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis
title_short The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis
title_full The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis
title_fullStr The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis
title_full_unstemmed The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis
title_sort signalling receptor mcam coordinates apical-basal polarity and planar cell polarity during morphogenesis
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/ab204da3ad6b440d8494627f04efac77
work_keys_str_mv AT qiangao thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT junfengzhang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT xiumeiwang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT yingliu thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT rongqiaohe thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT xingfengliu thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT feiwang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT jingfeng thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT donglingyang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT zhaoqingwang thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT anmingmeng thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT xiyunyan thesignallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT qiangao signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT junfengzhang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT xiumeiwang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT yingliu signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT rongqiaohe signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT xingfengliu signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT feiwang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT jingfeng signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT donglingyang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT zhaoqingwang signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT anmingmeng signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
AT xiyunyan signallingreceptormcamcoordinatesapicalbasalpolarityandplanarcellpolarityduringmorphogenesis
_version_ 1718390191302901760