The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis

It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB polarity via FGF signallingin vitroand in zebrafish.

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Detalles Bibliográficos
Autores principales: Qian Gao, Junfeng Zhang, Xiumei Wang, Ying Liu, Rongqiao He, Xingfeng Liu, Fei Wang, Jing Feng, Dongling Yang, Zhaoqing Wang, Anming Meng, Xiyun Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/ab204da3ad6b440d8494627f04efac77
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