VEGF, HIF-1α expression and MVD as an angiogenic network in familial breast cancer.

VEGF, HIF-1α expression and MVD as an angiogenic network in familial breast cancer.

Angiogenesis, which plays an important role in tumor growth and progression of breast cancer, is regulated by a balance between pro- and anti-angiogenic factors. Expression of vascular endothelial growth factor (VEGF) is up-regulated during hypoxia by hypoxia-inducible factor-1α (HIF-1α). It is know...

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Autores principales: Concetta Saponaro, Andrea Malfettone, Girolamo Ranieri, Katia Danza, Giovanni Simone, Angelo Paradiso, Anita Mangia
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/ab26d5908b67434d95e177b60285c75f
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