Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors
Transcriptional factors (TFs) bind in a combinatorial fashion to specify the on-and-off states of genes in a complex and redundant regulatory network. Here, the authors construct the transcription regulatory network in maize leaf using 104 TFs ChIP-seq data and train machine learning models to predi...
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Nature Portfolio
2020
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oai:doaj.org-article:ab27a8e4e9b64591b6b5f6f82b51efc62021-12-02T19:16:24ZReconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors10.1038/s41467-020-18832-82041-1723https://doaj.org/article/ab27a8e4e9b64591b6b5f6f82b51efc62020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18832-8https://doaj.org/toc/2041-1723Transcriptional factors (TFs) bind in a combinatorial fashion to specify the on-and-off states of genes in a complex and redundant regulatory network. Here, the authors construct the transcription regulatory network in maize leaf using 104 TFs ChIP-seq data and train machine learning models to predict TF binding and colocalization.Xiaoyu TuMaría Katherine Mejía-GuerraJose A. Valdes FrancoDavid TzengPo-Yu ChuWei ShenYingying WeiXiuru DaiPinghua LiEdward S. BucklerSilin ZhongNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q Xiaoyu Tu María Katherine Mejía-Guerra Jose A. Valdes Franco David Tzeng Po-Yu Chu Wei Shen Yingying Wei Xiuru Dai Pinghua Li Edward S. Buckler Silin Zhong Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors |
description |
Transcriptional factors (TFs) bind in a combinatorial fashion to specify the on-and-off states of genes in a complex and redundant regulatory network. Here, the authors construct the transcription regulatory network in maize leaf using 104 TFs ChIP-seq data and train machine learning models to predict TF binding and colocalization. |
format |
article |
author |
Xiaoyu Tu María Katherine Mejía-Guerra Jose A. Valdes Franco David Tzeng Po-Yu Chu Wei Shen Yingying Wei Xiuru Dai Pinghua Li Edward S. Buckler Silin Zhong |
author_facet |
Xiaoyu Tu María Katherine Mejía-Guerra Jose A. Valdes Franco David Tzeng Po-Yu Chu Wei Shen Yingying Wei Xiuru Dai Pinghua Li Edward S. Buckler Silin Zhong |
author_sort |
Xiaoyu Tu |
title |
Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors |
title_short |
Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors |
title_full |
Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors |
title_fullStr |
Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors |
title_full_unstemmed |
Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors |
title_sort |
reconstructing the maize leaf regulatory network using chip-seq data of 104 transcription factors |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/ab27a8e4e9b64591b6b5f6f82b51efc6 |
work_keys_str_mv |
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1718376930231713792 |