Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.

Neonicotinoid pesticides undermine pollinating insects including bumblebees. However, we have previously shown that mitochondrial damage induced by neonicotinoids can be corrected by 670nm light exposure. But we do not know if this protection extends to immunity or what the minimum effective level o...

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Autores principales:	Michael Barry Powner, Graham Priestley, Chris Hogg, Glen Jeffery
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ab27c18998b24963a2d6f38c561fde8d
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spelling	oai:doaj.org-article:ab27c18998b24963a2d6f38c561fde8d2021-12-02T20:19:30ZImproved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.1932-620310.1371/journal.pone.0256581https://doaj.org/article/ab27c18998b24963a2d6f38c561fde8d2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0256581https://doaj.org/toc/1932-6203Neonicotinoid pesticides undermine pollinating insects including bumblebees. However, we have previously shown that mitochondrial damage induced by neonicotinoids can be corrected by 670nm light exposure. But we do not know if this protection extends to immunity or what the minimum effective level of 670nm light exposure is necessary for protection. We use whole body bee respiration in vivo as a metric of neonicotinoid damage and assess the amount of light exposure needed to correct it. We reveal that only 1 min of 670nm exposure is sufficient to correct respiratory deficits induced by pesticide and that this also completely repairs damaged immunocompetence measured by haemocyte counts and the antibacterial action of hemolymph. Further, this single 1 min exposure remains effective for 3-6 days. Longer exposures were not more effective. Such data are key for development of protective light strategies that can be delivered by relatively small economic devices placed in hives.Michael Barry PownerGraham PriestleyChris HoggGlen JefferyPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0256581 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Michael Barry Powner Graham Priestley Chris Hogg Glen Jeffery Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.
description	Neonicotinoid pesticides undermine pollinating insects including bumblebees. However, we have previously shown that mitochondrial damage induced by neonicotinoids can be corrected by 670nm light exposure. But we do not know if this protection extends to immunity or what the minimum effective level of 670nm light exposure is necessary for protection. We use whole body bee respiration in vivo as a metric of neonicotinoid damage and assess the amount of light exposure needed to correct it. We reveal that only 1 min of 670nm exposure is sufficient to correct respiratory deficits induced by pesticide and that this also completely repairs damaged immunocompetence measured by haemocyte counts and the antibacterial action of hemolymph. Further, this single 1 min exposure remains effective for 3-6 days. Longer exposures were not more effective. Such data are key for development of protective light strategies that can be delivered by relatively small economic devices placed in hives.
format	article
author	Michael Barry Powner Graham Priestley Chris Hogg Glen Jeffery
author_facet	Michael Barry Powner Graham Priestley Chris Hogg Glen Jeffery
author_sort	Michael Barry Powner
title	Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.
title_short	Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.
title_full	Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.
title_fullStr	Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.
title_full_unstemmed	Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.
title_sort	improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/ab27c18998b24963a2d6f38c561fde8d
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Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.

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