The purinergic receptor antagonist oxidized adenosine triphosphate suppresses immune-mediated corneal allograft rejection

Abstract Adenosine triphosphate (ATP) is released into the extracellular environment during transplantation, and acts via purinergic receptors to amplify the alloimmune response. Here, using a well-established murine model of allogeneic corneal transplantation, we investigated the immunomodulatory m...

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Autores principales: William Foulsham, Sharad K. Mittal, Takeshi Nakao, Giulia Coco, Yukako Taketani, Sunil K. Chauhan, Reza Dana
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ab2e2f2678754b1596ab77c1e6dae7fd
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