Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation

Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation

NPM1 gene mutation is a founding event in acute myeloid leukaemia. Here, the authors find that at relapse, some patients lose the NPM1 mutation and show distinct mutational and gene expression patterns, highlighting a potential route for relapse.

Guardado en:
Detalles Bibliográficos
Autores principales: Sibylle Cocciardi, Anna Dolnik, Silke Kapp-Schwoerer, Frank G. Rücker, Susanne Lux, Tamara J. Blätte, Sabrina Skambraks, Jan Krönke, Florian H. Heidel, Tina M. Schnöder, Andrea Corbacioglu, Verena I. Gaidzik, Peter Paschka, Veronica Teleanu, Gudrun Göhring, Felicitas Thol, Michael Heuser, Arnold Ganser, Daniela Weber, Eric Sträng, Hans A. Kestler, Hartmut Döhner, Lars Bullinger, Konstanze Döhner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/ab42b55dd8f048919990526549391171
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares