Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria

Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria

Here, the authors identify signatures of miRNA expression differentiation associated with Plasmodium falciparum infection and parasitemia in a longitudinal pediatric cohort in Burkina Faso. In particular, expression of several miRNAs known to promote lymphocyte cell death is affected during infectio...

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Autores principales: Mame Massar Dieng, Aïssatou Diawara, Vinu Manikandan, Hala Tamim El Jarkass, Samuel Sindié Sermé, Salif Sombié, Aïssata Barry, Sam Aboubacar Coulibaly, Amidou Diarra, Nizar Drou, Marc Arnoux, Ayman Yousif, Alfred B. Tiono, Sodiomon B. Sirima, Issiaka Soulama, Youssef Idaghdour
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ab455e5318384660ba588434b292c602
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Sumario:Here, the authors identify signatures of miRNA expression differentiation associated with Plasmodium falciparum infection and parasitemia in a longitudinal pediatric cohort in Burkina Faso. In particular, expression of several miRNAs known to promote lymphocyte cell death is affected during infection.

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