Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria

Here, the authors identify signatures of miRNA expression differentiation associated with Plasmodium falciparum infection and parasitemia in a longitudinal pediatric cohort in Burkina Faso. In particular, expression of several miRNAs known to promote lymphocyte cell death is affected during infectio...

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Autores principales:	Mame Massar Dieng, Aïssatou Diawara, Vinu Manikandan, Hala Tamim El Jarkass, Samuel Sindié Sermé, Salif Sombié, Aïssata Barry, Sam Aboubacar Coulibaly, Amidou Diarra, Nizar Drou, Marc Arnoux, Ayman Yousif, Alfred B. Tiono, Sodiomon B. Sirima, Issiaka Soulama, Youssef Idaghdour
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ab455e5318384660ba588434b292c602
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spelling	oai:doaj.org-article:ab455e5318384660ba588434b292c6022021-12-02T18:37:29ZIntegrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria10.1038/s41467-020-18915-62041-1723https://doaj.org/article/ab455e5318384660ba588434b292c6022020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18915-6https://doaj.org/toc/2041-1723Here, the authors identify signatures of miRNA expression differentiation associated with Plasmodium falciparum infection and parasitemia in a longitudinal pediatric cohort in Burkina Faso. In particular, expression of several miRNAs known to promote lymphocyte cell death is affected during infection.Mame Massar DiengAïssatou DiawaraVinu ManikandanHala Tamim El JarkassSamuel Sindié SerméSalif SombiéAïssata BarrySam Aboubacar CoulibalyAmidou DiarraNizar DrouMarc ArnouxAyman YousifAlfred B. TionoSodiomon B. SirimaIssiaka SoulamaYoussef IdaghdourNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mame Massar Dieng Aïssatou Diawara Vinu Manikandan Hala Tamim El Jarkass Samuel Sindié Sermé Salif Sombié Aïssata Barry Sam Aboubacar Coulibaly Amidou Diarra Nizar Drou Marc Arnoux Ayman Yousif Alfred B. Tiono Sodiomon B. Sirima Issiaka Soulama Youssef Idaghdour Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
description	Here, the authors identify signatures of miRNA expression differentiation associated with Plasmodium falciparum infection and parasitemia in a longitudinal pediatric cohort in Burkina Faso. In particular, expression of several miRNAs known to promote lymphocyte cell death is affected during infection.
format	article
author	Mame Massar Dieng Aïssatou Diawara Vinu Manikandan Hala Tamim El Jarkass Samuel Sindié Sermé Salif Sombié Aïssata Barry Sam Aboubacar Coulibaly Amidou Diarra Nizar Drou Marc Arnoux Ayman Yousif Alfred B. Tiono Sodiomon B. Sirima Issiaka Soulama Youssef Idaghdour
author_facet	Mame Massar Dieng Aïssatou Diawara Vinu Manikandan Hala Tamim El Jarkass Samuel Sindié Sermé Salif Sombié Aïssata Barry Sam Aboubacar Coulibaly Amidou Diarra Nizar Drou Marc Arnoux Ayman Yousif Alfred B. Tiono Sodiomon B. Sirima Issiaka Soulama Youssef Idaghdour
author_sort	Mame Massar Dieng
title	Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
title_short	Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
title_full	Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
title_fullStr	Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
title_full_unstemmed	Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
title_sort	integrative genomic analysis reveals mechanisms of immune evasion in p. falciparum malaria
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ab455e5318384660ba588434b292c602
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Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria

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