Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells

Secreted proteins present a rich resource of potential cancer biomarkers. Here, the authors use mass spectrometry to analyze secretome remodeling in pulmonary neuroendocrine lung cancer cell lines and validate potential biomarkers and therapeutic targets in vitro and in mouse models.

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Autores principales:	Xu-Dong Wang, Rongkuan Hu, Qing Ding, Trisha K. Savage, Kenneth E. Huffman, Noelle Williams, Melanie H. Cobb, John D. Minna, Jane E. Johnson, Yonghao Yu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ab493e2c25ce4d6f9e28ead2e5b28542
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spelling	oai:doaj.org-article:ab493e2c25ce4d6f9e28ead2e5b285422021-12-02T14:35:37ZSubtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells10.1038/s41467-019-11153-52041-1723https://doaj.org/article/ab493e2c25ce4d6f9e28ead2e5b285422019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11153-5https://doaj.org/toc/2041-1723Secreted proteins present a rich resource of potential cancer biomarkers. Here, the authors use mass spectrometry to analyze secretome remodeling in pulmonary neuroendocrine lung cancer cell lines and validate potential biomarkers and therapeutic targets in vitro and in mouse models.Xu-Dong WangRongkuan HuQing DingTrisha K. SavageKenneth E. HuffmanNoelle WilliamsMelanie H. CobbJohn D. MinnaJane E. JohnsonYonghao YuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xu-Dong Wang Rongkuan Hu Qing Ding Trisha K. Savage Kenneth E. Huffman Noelle Williams Melanie H. Cobb John D. Minna Jane E. Johnson Yonghao Yu Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
description	Secreted proteins present a rich resource of potential cancer biomarkers. Here, the authors use mass spectrometry to analyze secretome remodeling in pulmonary neuroendocrine lung cancer cell lines and validate potential biomarkers and therapeutic targets in vitro and in mouse models.
format	article
author	Xu-Dong Wang Rongkuan Hu Qing Ding Trisha K. Savage Kenneth E. Huffman Noelle Williams Melanie H. Cobb John D. Minna Jane E. Johnson Yonghao Yu
author_facet	Xu-Dong Wang Rongkuan Hu Qing Ding Trisha K. Savage Kenneth E. Huffman Noelle Williams Melanie H. Cobb John D. Minna Jane E. Johnson Yonghao Yu
author_sort	Xu-Dong Wang
title	Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
title_short	Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
title_full	Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
title_fullStr	Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
title_full_unstemmed	Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
title_sort	subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ab493e2c25ce4d6f9e28ead2e5b28542
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Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells

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