Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells

Secreted proteins present a rich resource of potential cancer biomarkers. Here, the authors use mass spectrometry to analyze secretome remodeling in pulmonary neuroendocrine lung cancer cell lines and validate potential biomarkers and therapeutic targets in vitro and in mouse models.

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Auteurs principaux: Xu-Dong Wang, Rongkuan Hu, Qing Ding, Trisha K. Savage, Kenneth E. Huffman, Noelle Williams, Melanie H. Cobb, John D. Minna, Jane E. Johnson, Yonghao Yu
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/ab493e2c25ce4d6f9e28ead2e5b28542
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