In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition

During repair, development, or cancer metastasis, epithelial cells can become migratory through partial or full epithelial to mesenchymal transition (EMT). Here, the authors report that differentiated epithelial collectives may undergo cooperative and collective migration without evidence of partial...

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Autores principales: Jennifer A. Mitchel, Amit Das, Michael J. O’Sullivan, Ian T. Stancil, Stephen J. DeCamp, Stephan Koehler, Oscar H. Ocaña, James P. Butler, Jeffrey J. Fredberg, M. Angela Nieto, Dapeng Bi, Jin-Ah Park
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ab4af25389c54c6284d0fdfba0eb6c62
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spelling oai:doaj.org-article:ab4af25389c54c6284d0fdfba0eb6c622021-12-02T18:37:17ZIn primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition10.1038/s41467-020-18841-72041-1723https://doaj.org/article/ab4af25389c54c6284d0fdfba0eb6c622020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18841-7https://doaj.org/toc/2041-1723During repair, development, or cancer metastasis, epithelial cells can become migratory through partial or full epithelial to mesenchymal transition (EMT). Here, the authors report that differentiated epithelial collectives may undergo cooperative and collective migration without evidence of partial EMT through an unjamming transition (UJT).Jennifer A. MitchelAmit DasMichael J. O’SullivanIan T. StancilStephen J. DeCampStephan KoehlerOscar H. OcañaJames P. ButlerJeffrey J. FredbergM. Angela NietoDapeng BiJin-Ah ParkNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jennifer A. Mitchel
Amit Das
Michael J. O’Sullivan
Ian T. Stancil
Stephen J. DeCamp
Stephan Koehler
Oscar H. Ocaña
James P. Butler
Jeffrey J. Fredberg
M. Angela Nieto
Dapeng Bi
Jin-Ah Park
In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
description During repair, development, or cancer metastasis, epithelial cells can become migratory through partial or full epithelial to mesenchymal transition (EMT). Here, the authors report that differentiated epithelial collectives may undergo cooperative and collective migration without evidence of partial EMT through an unjamming transition (UJT).
format article
author Jennifer A. Mitchel
Amit Das
Michael J. O’Sullivan
Ian T. Stancil
Stephen J. DeCamp
Stephan Koehler
Oscar H. Ocaña
James P. Butler
Jeffrey J. Fredberg
M. Angela Nieto
Dapeng Bi
Jin-Ah Park
author_facet Jennifer A. Mitchel
Amit Das
Michael J. O’Sullivan
Ian T. Stancil
Stephen J. DeCamp
Stephan Koehler
Oscar H. Ocaña
James P. Butler
Jeffrey J. Fredberg
M. Angela Nieto
Dapeng Bi
Jin-Ah Park
author_sort Jennifer A. Mitchel
title In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
title_short In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
title_full In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
title_fullStr In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
title_full_unstemmed In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
title_sort in primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ab4af25389c54c6284d0fdfba0eb6c62
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