Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging
Abstract Cerebral aneurysms are potentially life threatening and nowadays treated by a catheter-guided coiling or by a neurosurgical clipping intervention. Here, we propose a helically shaped magnetic micro-robot, which can be steered by magnetic fields in an untethered manner and could be applied f...
Guardado en:
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/ab54bde244bd4ddb91ffcd4de91f0f13 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:ab54bde244bd4ddb91ffcd4de91f0f13 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:ab54bde244bd4ddb91ffcd4de91f0f132021-12-02T15:22:57ZNavigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging10.1038/s41598-021-93323-42045-2322https://doaj.org/article/ab54bde244bd4ddb91ffcd4de91f0f132021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93323-4https://doaj.org/toc/2045-2322Abstract Cerebral aneurysms are potentially life threatening and nowadays treated by a catheter-guided coiling or by a neurosurgical clipping intervention. Here, we propose a helically shaped magnetic micro-robot, which can be steered by magnetic fields in an untethered manner and could be applied for a novel coiling procedure. This is shown by navigating the micro-robot through an additively manufactured phantom of a human cerebral aneurysm. The magnetic fields are applied with a magnetic particle imaging (MPI) scanner, which allows for the navigation and tomographic visualization by the same machine. With MPI the actuation process can be visualized with a localization accuracy of 0.68 mm and an angiogram can be acquired both without any radiation exposure. First in-vitro phantom experiments are presented, showing an idea of a robot conducted treatment of cerebral aneurysms.Anna C. BakeneckerAnselm von GladissHannes SchwenkeAndré BehrendsThomas FriedrichKerstin Lüdtke-BuzugAlexander NeumannJoerg BarkhausenFranz WegnerThorsten M. BuzugNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Anna C. Bakenecker Anselm von Gladiss Hannes Schwenke André Behrends Thomas Friedrich Kerstin Lüdtke-Buzug Alexander Neumann Joerg Barkhausen Franz Wegner Thorsten M. Buzug Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging |
| description |
Abstract Cerebral aneurysms are potentially life threatening and nowadays treated by a catheter-guided coiling or by a neurosurgical clipping intervention. Here, we propose a helically shaped magnetic micro-robot, which can be steered by magnetic fields in an untethered manner and could be applied for a novel coiling procedure. This is shown by navigating the micro-robot through an additively manufactured phantom of a human cerebral aneurysm. The magnetic fields are applied with a magnetic particle imaging (MPI) scanner, which allows for the navigation and tomographic visualization by the same machine. With MPI the actuation process can be visualized with a localization accuracy of 0.68 mm and an angiogram can be acquired both without any radiation exposure. First in-vitro phantom experiments are presented, showing an idea of a robot conducted treatment of cerebral aneurysms. |
| format |
article |
| author |
Anna C. Bakenecker Anselm von Gladiss Hannes Schwenke André Behrends Thomas Friedrich Kerstin Lüdtke-Buzug Alexander Neumann Joerg Barkhausen Franz Wegner Thorsten M. Buzug |
| author_facet |
Anna C. Bakenecker Anselm von Gladiss Hannes Schwenke André Behrends Thomas Friedrich Kerstin Lüdtke-Buzug Alexander Neumann Joerg Barkhausen Franz Wegner Thorsten M. Buzug |
| author_sort |
Anna C. Bakenecker |
| title |
Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging |
| title_short |
Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging |
| title_full |
Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging |
| title_fullStr |
Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging |
| title_full_unstemmed |
Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging |
| title_sort |
navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/ab54bde244bd4ddb91ffcd4de91f0f13 |
| work_keys_str_mv |
AT annacbakenecker navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT anselmvongladiss navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT hannesschwenke navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT andrebehrends navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT thomasfriedrich navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT kerstinludtkebuzug navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT alexanderneumann navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT joergbarkhausen navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT franzwegner navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging AT thorstenmbuzug navigationofamagneticmicrorobotthroughacerebralaneurysmphantomwithmagneticparticleimaging |
| _version_ |
1718387396674846720 |