Lack of PPARγ in myeloid cells confers resistance to Listeria monocytogenes infection.

Lack of PPARγ in myeloid cells confers resistance to Listeria monocytogenes infection.

The peroxisomal proliferator-activated receptor γ (PPARγ) is a nuclear receptor that controls inflammation and immunity. Innate immune defense against bacterial infection appears to be compromised by PPARγ. The relevance of PPARγ in myeloid cells, that organize anti-bacterial immunity, for the outco...

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Autores principales: Zeinab Abdullah, Sergej Geiger, Andrea Nino-Castro, Jan P Böttcher, Eugenia Muraliv, Moritz Gaidt, Frank A Schildberg, Kati Riethausen, Juliane Flossdorf, Wolfgang Krebs, Trinad Chakraborty, Christian Kurts, Joachim L Schultze, Percy A Knolle, Luisa Klotz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ab5a2bdd297c4eec8bb36425ff0d1cf5
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