Dexmedetomidine inhibits the NF-κB pathway and NLRP3 inflammasome to attenuate papain-induced osteoarthritis in rats

Context: Dexmedetomidine (Dex) has been reported to have an anti-inflammatory effect. However, its role on osteoarthritis (OA) has not been explored. Objective: This study investigates the effect of Dex on OA rat model induced by papain. Materials and methods: The OA Wistar rat model was induced by...

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Auteurs principaux: Fang Cheng, Feng-Feng Yan, Yue-Peng Liu, Yan Cong, Ke-Fu Sun, Xue-Ming He
Format: article
Langue:EN
Publié: Taylor & Francis Group 2019
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Accès en ligne:https://doaj.org/article/ab64ca84b5ff4eb89df9617460e3d4c3
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