CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES

We are studied the 15 patients with autoimmune liver diseases and 36 patients without autoimmune pathology found the diagnostic value of antinuclear and antimitochondrial autoantibodies (AMA-M2) tests, and antibodies to asialoglycoprotein receptor (anti-ASGPR). Based on the ROC analysis showed that...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	V. V. Bazarnyi, E. Yu. Mikhailova, E. A. Partylova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2015
Materias:	autoimmune hepatitis primary biliary cirrhosis autoantibodies Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/ab6646f14b1249389ff3094dbd6751fe
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ab6646f14b1249389ff3094dbd6751fe
record_format	dspace
spelling	oai:doaj.org-article:ab6646f14b1249389ff3094dbd6751fe2021-11-18T08:03:44ZCLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES1563-06252313-741X10.15789/1563-0625-2015-1-93-96https://doaj.org/article/ab6646f14b1249389ff3094dbd6751fe2015-03-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/814https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XWe are studied the 15 patients with autoimmune liver diseases and 36 patients without autoimmune pathology found the diagnostic value of antinuclear and antimitochondrial autoantibodies (AMA-M2) tests, and antibodies to asialoglycoprotein receptor (anti-ASGPR). Based on the ROC analysis showed that the diagnostic sensitivity and diagnostic specificity of AMA-M2 was 73% and 100% and for anti-ASGPR – 60% and 77%, respectively. Therefore, the test for anti-ASGPR in autoimmune diseases of the liver showed no advantages over standart tests, and its using in clinical practice requires clarification.V. V. BazarnyiE. Yu. MikhailovaE. A. PartylovaSPb RAACIarticleautoimmune hepatitisprimary biliary cirrhosisautoantibodiesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 17, Iss 1, Pp 93-96 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	autoimmune hepatitis primary biliary cirrhosis autoantibodies Immunologic diseases. Allergy RC581-607
spellingShingle	autoimmune hepatitis primary biliary cirrhosis autoantibodies Immunologic diseases. Allergy RC581-607 V. V. Bazarnyi E. Yu. Mikhailova E. A. Partylova CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES
description	We are studied the 15 patients with autoimmune liver diseases and 36 patients without autoimmune pathology found the diagnostic value of antinuclear and antimitochondrial autoantibodies (AMA-M2) tests, and antibodies to asialoglycoprotein receptor (anti-ASGPR). Based on the ROC analysis showed that the diagnostic sensitivity and diagnostic specificity of AMA-M2 was 73% and 100% and for anti-ASGPR – 60% and 77%, respectively. Therefore, the test for anti-ASGPR in autoimmune diseases of the liver showed no advantages over standart tests, and its using in clinical practice requires clarification.
format	article
author	V. V. Bazarnyi E. Yu. Mikhailova E. A. Partylova
author_facet	V. V. Bazarnyi E. Yu. Mikhailova E. A. Partylova
author_sort	V. V. Bazarnyi
title	CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES
title_short	CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES
title_full	CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES
title_fullStr	CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES
title_full_unstemmed	CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES
title_sort	clinical diagnostic value of autoantibodies in the diagnosis of autoimmune liver diseases
publisher	SPb RAACI
publishDate	2015
url	https://doaj.org/article/ab6646f14b1249389ff3094dbd6751fe
work_keys_str_mv	AT vvbazarnyi clinicaldiagnosticvalueofautoantibodiesinthediagnosisofautoimmuneliverdiseases AT eyumikhailova clinicaldiagnosticvalueofautoantibodiesinthediagnosisofautoimmuneliverdiseases AT eapartylova clinicaldiagnosticvalueofautoantibodiesinthediagnosisofautoimmuneliverdiseases
_version_	1718422440881684480

CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES

Ejemplares similares