HIV infection disrupts the sympatric host-pathogen relationship in human tuberculosis.

HIV infection disrupts the sympatric host-pathogen relationship in human tuberculosis.

The phylogeographic population structure of Mycobacterium tuberculosis suggests local adaptation to sympatric human populations. We hypothesized that HIV infection, which induces immunodeficiency, will alter the sympatric relationship between M. tuberculosis and its human host. To test this hypothes...

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Autores principales: Lukas Fenner, Matthias Egger, Thomas Bodmer, Hansjakob Furrer, Marie Ballif, Manuel Battegay, Peter Helbling, Jan Fehr, Thomas Gsponer, Hans L Rieder, Marcel Zwahlen, Matthias Hoffmann, Enos Bernasconi, Matthias Cavassini, Alexandra Calmy, Marisa Dolina, Reno Frei, Jean-Paul Janssens, Sonia Borrell, David Stucki, Jacques Schrenzel, Erik C Böttger, Sebastien Gagneux, Swiss HIV Cohort and Molecular Epidemiology of Tuberculosis Study Groups
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/ab6dde2d7caa456985fc05a109784590
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