Application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers

Yuri An,1 Jong Wook Jeon,2 Kihwan Kwon,3 Chulhee Choi1 1Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea; 2Acupuncture, Moxibustion and Meridian Research Centre, Korea Institute of Oriental Medicine, Daejeon, South Korea; 3Department of Cardiology, College of Medicine, Ewha Woma...

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Autores principales:	An Y, Jeon JW, Kwon K, Choi C
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/ab896a42dfe942428ba2078006a51a66
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spelling	oai:doaj.org-article:ab896a42dfe942428ba2078006a51a662021-12-02T05:09:58ZApplication of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers1179-1470https://doaj.org/article/ab896a42dfe942428ba2078006a51a662014-02-01T00:00:00Zhttp://www.dovepress.com/application-of-dynamic-indocyanine-green-perfusion-imaging-for-evaluat-a15890https://doaj.org/toc/1179-1470 Yuri An,1 Jong Wook Jeon,2 Kihwan Kwon,3 Chulhee Choi1 1Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea; 2Acupuncture, Moxibustion and Meridian Research Centre, Korea Institute of Oriental Medicine, Daejeon, South Korea; 3Department of Cardiology, College of Medicine, Ewha Womans University, Seoul, Korea Background: Even though acupuncture has long been used for alleviating symptoms related to vascular insufficiency, the clinical effect of acupuncture on peripheral circulation has not been fully confirmed. In this study, we investigated whether a near-infrared optical imaging-based method can be used to evaluate the efficacy of the acupuncture procedure to induce changes in peripheral tissue perfusion. Methods: Two normal, healthy controls were treated with acupuncture on two acupoints (LI-4 and SI-3) three times within 1 week. At the first and third visits, participants were examined using indocyanine green (ICG) perfusion imaging before and 10 minutes after the acupuncture procedure. Blood perfusion of the hands was determined after intravenous bolus injection of ICG and dynamic analysis of the fluorescence signals by near-infrared imaging system. Results: The blood perfusion rates of the hands were markedly increased immediately after acupuncture at the first trial in both cases. The baseline perfusion rates of the hands measured at the third visit were higher compared to the original basal level in one case; there was no difference in baseline perfusion rates of both hands in another case. In both cases, there was no acute effect of acupuncture on hand perfusion at the third trial. Conclusions: These results collectively suggest a potential of the ICG perfusion imaging as an effective evaluation tool to validate the vasoactive effect of acupuncture. Keywords: vasodilation, blood perfusion, imaging, Raynaud syndromeAn YJeon JWKwon KChoi CDove Medical PressarticleMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2014, Iss default, Pp 17-21 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical technology R855-855.5
spellingShingle	Medical technology R855-855.5 An Y Jeon JW Kwon K Choi C Application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers
description	Yuri An,1 Jong Wook Jeon,2 Kihwan Kwon,3 Chulhee Choi1 1Department of Bio and Brain Engineering, KAIST, Daejeon, South Korea; 2Acupuncture, Moxibustion and Meridian Research Centre, Korea Institute of Oriental Medicine, Daejeon, South Korea; 3Department of Cardiology, College of Medicine, Ewha Womans University, Seoul, Korea Background: Even though acupuncture has long been used for alleviating symptoms related to vascular insufficiency, the clinical effect of acupuncture on peripheral circulation has not been fully confirmed. In this study, we investigated whether a near-infrared optical imaging-based method can be used to evaluate the efficacy of the acupuncture procedure to induce changes in peripheral tissue perfusion. Methods: Two normal, healthy controls were treated with acupuncture on two acupoints (LI-4 and SI-3) three times within 1 week. At the first and third visits, participants were examined using indocyanine green (ICG) perfusion imaging before and 10 minutes after the acupuncture procedure. Blood perfusion of the hands was determined after intravenous bolus injection of ICG and dynamic analysis of the fluorescence signals by near-infrared imaging system. Results: The blood perfusion rates of the hands were markedly increased immediately after acupuncture at the first trial in both cases. The baseline perfusion rates of the hands measured at the third visit were higher compared to the original basal level in one case; there was no difference in baseline perfusion rates of both hands in another case. In both cases, there was no acute effect of acupuncture on hand perfusion at the third trial. Conclusions: These results collectively suggest a potential of the ICG perfusion imaging as an effective evaluation tool to validate the vasoactive effect of acupuncture. Keywords: vasodilation, blood perfusion, imaging, Raynaud syndrome
format	article
author	An Y Jeon JW Kwon K Choi C
author_facet	An Y Jeon JW Kwon K Choi C
author_sort	An Y
title	Application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers
title_short	Application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers
title_full	Application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers
title_fullStr	Application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers
title_full_unstemmed	Application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers
title_sort	application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/ab896a42dfe942428ba2078006a51a66
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_version_	1718400552725905408

Application of dynamic indocyanine green perfusion imaging for evaluation of vasoactive effect of acupuncture: a preliminary follow-up study on normal healthy volunteers

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