Endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.

<h4>Background</h4>The endoscopic transsphenoidal approach is an efficient minimally invasive procedure for removal of pituitary tumors that can be accomplished through a one-hand or two-hand approach. The one-hand procedure through one nostril is more intuitive for surgeons, but maneuve...

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Autores principales:	Jiun-Lin Yan, Chen-Nen Chang, Pin-Yuan Chen
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ab9a40cb49f0413e874e29686dfde043
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spelling	oai:doaj.org-article:ab9a40cb49f0413e874e29686dfde0432021-12-02T20:18:34ZEndoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.1932-620310.1371/journal.pone.0255599https://doaj.org/article/ab9a40cb49f0413e874e29686dfde0432021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255599https://doaj.org/toc/1932-6203<h4>Background</h4>The endoscopic transsphenoidal approach is an efficient minimally invasive procedure for removal of pituitary tumors that can be accomplished through a one-hand or two-hand approach. The one-hand procedure through one nostril is more intuitive for surgeons, but maneuvering the instruments can be restrictive. The two-hand procedure using a one-and-half nostril approach provides more precise manipulation. This study aimed to compare the surgical outcomes of one-hand/mono-nostril and two-hand/one-and-half nostril surgeries for resection of large pituitary tumors by a single neurosurgeon.<h4>Materials and methods</h4>The surgical data of 78 consecutive cases with pituitary macroadenoma (diameter >1 cm) were reviewed retrospectively. Altogether, 30 cases received one-hand/mono-nostril surgery, while 48 cases received two-hand/one-and-half nostril surgery. Postoperative outcomes of the two operations were compared.<h4>Results</h4>The operative time, hospital stay, residual rate of pituitary macroadenoma, visual field, surgical complications, and re-operative rates were slightly improved in the two-hand/one-and-half nostril surgery group compared with that in the one-hand/mono-nostril surgery group (all p>0.05). However, postoperative hypopituitarism was less frequent (1/48; 2.0%) with the two-hand/one-and-half nostril approach than with the mono-nostril approach (p = 0.004). Similar surgical outcomes were found in all patients with either small or large pituitary tumors, except that the difference in postoperative improvement in visual field change reached statistical significance (p = 0.044).<h4>Conclusion</h4>A single-surgeon endoscopic endonasal transsphenoidal surgery with two-hand/one-and-half nostril approach is an effective and safe procedure for removal of large pituitary tumors.Jiun-Lin YanChen-Nen ChangPin-Yuan ChenPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255599 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jiun-Lin Yan Chen-Nen Chang Pin-Yuan Chen Endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.
description	<h4>Background</h4>The endoscopic transsphenoidal approach is an efficient minimally invasive procedure for removal of pituitary tumors that can be accomplished through a one-hand or two-hand approach. The one-hand procedure through one nostril is more intuitive for surgeons, but maneuvering the instruments can be restrictive. The two-hand procedure using a one-and-half nostril approach provides more precise manipulation. This study aimed to compare the surgical outcomes of one-hand/mono-nostril and two-hand/one-and-half nostril surgeries for resection of large pituitary tumors by a single neurosurgeon.<h4>Materials and methods</h4>The surgical data of 78 consecutive cases with pituitary macroadenoma (diameter >1 cm) were reviewed retrospectively. Altogether, 30 cases received one-hand/mono-nostril surgery, while 48 cases received two-hand/one-and-half nostril surgery. Postoperative outcomes of the two operations were compared.<h4>Results</h4>The operative time, hospital stay, residual rate of pituitary macroadenoma, visual field, surgical complications, and re-operative rates were slightly improved in the two-hand/one-and-half nostril surgery group compared with that in the one-hand/mono-nostril surgery group (all p>0.05). However, postoperative hypopituitarism was less frequent (1/48; 2.0%) with the two-hand/one-and-half nostril approach than with the mono-nostril approach (p = 0.004). Similar surgical outcomes were found in all patients with either small or large pituitary tumors, except that the difference in postoperative improvement in visual field change reached statistical significance (p = 0.044).<h4>Conclusion</h4>A single-surgeon endoscopic endonasal transsphenoidal surgery with two-hand/one-and-half nostril approach is an effective and safe procedure for removal of large pituitary tumors.
format	article
author	Jiun-Lin Yan Chen-Nen Chang Pin-Yuan Chen
author_facet	Jiun-Lin Yan Chen-Nen Chang Pin-Yuan Chen
author_sort	Jiun-Lin Yan
title	Endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.
title_short	Endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.
title_full	Endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.
title_fullStr	Endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.
title_full_unstemmed	Endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.
title_sort	endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: a retrospective study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/ab9a40cb49f0413e874e29686dfde043
work_keys_str_mv	AT jiunlinyan endoscopictranssphenoidalsurgeryforresectionofpituitarymacroadenomaaretrospectivestudy AT chennenchang endoscopictranssphenoidalsurgeryforresectionofpituitarymacroadenomaaretrospectivestudy AT pinyuanchen endoscopictranssphenoidalsurgeryforresectionofpituitarymacroadenomaaretrospectivestudy
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Endoscopic transsphenoidal surgery for resection of pituitary macroadenoma: A retrospective study.

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