Distribution bias and biochemical characterization of TOP1MT single nucleotide variants
Abstract Mitochondrial topoisomerase I (TOP1MT) is a type IB topoisomerase encoded in the nucleus of vertebrate cells. In contrast to the other five human topoisomerases, TOP1MT possesses two high frequency single nucleotide variants (SNVs), rs11544484 (V256I, Minor Allele Frequency = 0.27) and rs22...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2017
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/ab9c848683b442378bbba0097b3e7468 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|