Effect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population

Katelynn E Weber,1 Andrea FR Fischl,2 Pamela J Murray,3 Baqiyyah N Conway1 1Department of Epidemiology, West Virginia University, Morgantown, WV, USA; 2University of Pittsburgh School of Nursing, Pittsburgh, PA, USA; 3Department of Pediatrics, West Virginia University, Morgantown, WV, USA Backgroun...

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Autores principales:	Weber KE, Fischl AFR, Murray PJ, Conway BN
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/aba3eadf852f40ff92caddb0620c3192
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spelling	oai:doaj.org-article:aba3eadf852f40ff92caddb0620c31922021-12-02T01:25:11ZEffect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population1178-7007https://doaj.org/article/aba3eadf852f40ff92caddb0620c31922014-09-01T00:00:00Zhttp://www.dovepress.com/effect-of-bmi-on-cardiovascular-and-metabolic-syndrome-risk-factors-in-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007 Katelynn E Weber,1 Andrea FR Fischl,2 Pamela J Murray,3 Baqiyyah N Conway1 1Department of Epidemiology, West Virginia University, Morgantown, WV, USA; 2University of Pittsburgh School of Nursing, Pittsburgh, PA, USA; 3Department of Pediatrics, West Virginia University, Morgantown, WV, USA Background: The purpose of this study was to characterize cardiovascular risk factors in a rural pediatric population by body mass index (BMI) category and the presence of the metabolic syndrome.Methods: Data on 13,018 children and adolescents (aged younger than 20 years) from West Virginia and Ohio in 2005–2006 were obtained from the C8 Health Project to determine the prevalence of overweight/obesity and the metabolic syndrome, which was then compared with National Health and Nutrition Examination Survey 2005–2006 data. Cardiovascular risk factors were assessed by age-standardized and sex-standardized BMI category (<85th, 85th–95th, >95th percentiles) and the presence of metabolic syndrome, defined as the presence of three or more of the following criteria: BMI >97th percentile, triglycerides >110 mg/dL, high-density lipoprotein cholesterol <40 mg/dL, and fasting blood glucose >110 mg/dL.Results: The population was 51% male and 95% white. The prevalence of overweight/obesity was 38% and metabolic syndrome was 4.6% in the C8 population, compared with a prevalence of 30% and 3.4%, respectively, within the National Health and Nutrition Examination Survey population. In our Appalachian population, a significant adverse trend across BMI categories was observed for lipids, insulin, inflammatory markers, white blood cell count, and C-reactive protein. Significant differences in these risk factors were seen among those with metabolic syndrome compared with those without metabolic syndrome.Conclusion: The increased prevalence of overweight/obesity and the metabolic syndrome along with the increase in cardiovascular risk factors in Appalachian children and adolescents, suggests a cohort that may develop earlier onset and possibly increased severity of cardiovascular disease and other complications associated with metabolic syndrome and obesity. Keywords: body mass index, cardiovascular, metabolic syndrome, risk factors, pediatric population, AppalachianWeber KEFischl AFRMurray PJConway BNDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2014, Iss default, Pp 445-453 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Weber KE Fischl AFR Murray PJ Conway BN Effect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population
description	Katelynn E Weber,1 Andrea FR Fischl,2 Pamela J Murray,3 Baqiyyah N Conway1 1Department of Epidemiology, West Virginia University, Morgantown, WV, USA; 2University of Pittsburgh School of Nursing, Pittsburgh, PA, USA; 3Department of Pediatrics, West Virginia University, Morgantown, WV, USA Background: The purpose of this study was to characterize cardiovascular risk factors in a rural pediatric population by body mass index (BMI) category and the presence of the metabolic syndrome.Methods: Data on 13,018 children and adolescents (aged younger than 20 years) from West Virginia and Ohio in 2005–2006 were obtained from the C8 Health Project to determine the prevalence of overweight/obesity and the metabolic syndrome, which was then compared with National Health and Nutrition Examination Survey 2005–2006 data. Cardiovascular risk factors were assessed by age-standardized and sex-standardized BMI category (<85th, 85th–95th, >95th percentiles) and the presence of metabolic syndrome, defined as the presence of three or more of the following criteria: BMI >97th percentile, triglycerides >110 mg/dL, high-density lipoprotein cholesterol <40 mg/dL, and fasting blood glucose >110 mg/dL.Results: The population was 51% male and 95% white. The prevalence of overweight/obesity was 38% and metabolic syndrome was 4.6% in the C8 population, compared with a prevalence of 30% and 3.4%, respectively, within the National Health and Nutrition Examination Survey population. In our Appalachian population, a significant adverse trend across BMI categories was observed for lipids, insulin, inflammatory markers, white blood cell count, and C-reactive protein. Significant differences in these risk factors were seen among those with metabolic syndrome compared with those without metabolic syndrome.Conclusion: The increased prevalence of overweight/obesity and the metabolic syndrome along with the increase in cardiovascular risk factors in Appalachian children and adolescents, suggests a cohort that may develop earlier onset and possibly increased severity of cardiovascular disease and other complications associated with metabolic syndrome and obesity. Keywords: body mass index, cardiovascular, metabolic syndrome, risk factors, pediatric population, Appalachian
format	article
author	Weber KE Fischl AFR Murray PJ Conway BN
author_facet	Weber KE Fischl AFR Murray PJ Conway BN
author_sort	Weber KE
title	Effect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population
title_short	Effect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population
title_full	Effect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population
title_fullStr	Effect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population
title_full_unstemmed	Effect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population
title_sort	effect of bmi on cardiovascular and metabolic syndrome risk factors in an appalachian pediatric population
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/aba3eadf852f40ff92caddb0620c3192
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Effect of BMI on cardiovascular and metabolic syndrome risk factors in an Appalachian pediatric population

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