Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel.

Given the worldwide burden of neglected tropical diseases, there is ongoing need to develop novel anthelmintic agents to strengthen the pipeline of drugs to combat these burdensome infections. Many diseases caused by parasitic flatworms are treated using the anthelmintic drug praziquantel (PZQ), emp...

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Bibliographic Details
Main Authors: Evgeny G Chulkov, Emery Smith, Claudia M Rohr, Nawal A Yahya, Sang-Kyu Park, Louis Scampavia, Timothy P Spicer, Jonathan S Marchant
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/abaa115946af4e45b4a03469ea0cec2b
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