A DNase from a Fungal Phytopathogen Is a Virulence Factor Likely Deployed as Counter Defense against Host-Secreted Extracellular DNA

ABSTRACT Histone-linked extracellular DNA (exDNA) is a component of neutrophil extracellular traps (NETs). NETs have been shown to play a role in immune response to bacteria, fungi, viruses, and protozoan parasites. Mutation of genes encoding group A Streptococcus extracellular DNases (exDNases) res...

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Autores principales: Hee-Jin Park, Weiwei Wang, Gilberto Curlango-Rivera, Zhongguo Xiong, Zeran Lin, David A. Huskey, Martha C. Hawes, Hans D. VanEtten, B. Gillian Turgeon
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/abab718eb8294da5b920b98073c95b7e
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