25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)

25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)

Abstract Background The study aim was to obtain epidemiological data on vitamin D levels for the pediatric population in Japan. We assessed the prevalence of vitamin D deficiency and insufficiency in 2-year-old Japanese children using data from a large ongoing birth cohort study. Methods Data for an...

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Autores principales: Limin Yang, Miori Sato, Mayako Saito-Abe, Makoto Irahara, Minaho Nishizato, Hatoko Sasaki, Mizuho Konishi, Kazue Ishitsuka, Hidetoshi Mezawa, Kiwako Yamamoto-Hanada, Yukihiro Ohya, for the Japan Environment and Children’s Study (JECS) Group)
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
25-Hydroxyvitamin D
Vitamin D
Deficiency
Insufficiency
Children
Cohort
Pediatrics
RJ1-570
Acceso en línea:https://doaj.org/article/abad2f05cf204aaa897f3daab4dc5395
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spelling oai:doaj.org-article:abad2f05cf204aaa897f3daab4dc53952021-12-05T12:21:18Z25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)10.1186/s12887-021-03005-31471-2431https://doaj.org/article/abad2f05cf204aaa897f3daab4dc53952021-12-01T00:00:00Zhttps://doi.org/10.1186/s12887-021-03005-3https://doaj.org/toc/1471-2431Abstract Background The study aim was to obtain epidemiological data on vitamin D levels for the pediatric population in Japan. We assessed the prevalence of vitamin D deficiency and insufficiency in 2-year-old Japanese children using data from a large ongoing birth cohort study. Methods Data for analysis was obtained from the Japan Environment and Children’s Study (JECS) and a Sub-Cohort Study (SCS) of JECS. We evaluated the children’s serum 25(OH) D levels by 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles, and the rates of vitamin D deficiency or insufficiency. We also presented a weighted prevalence rate for vitamin D deficiency or insufficiency among all children in JECS. Results After excluding children with missing 25(OH)D2 or 25(OH)D3 data, we analyzed 4655 remaining children, of whom 24.7% (95% CI, 23.5–26.0%) had vitamin D deficiency (< 20 ng/mL), and 51.3% (95% CI, 49.8–52.7%) were at risk of vitamin D insufficiency (20–30 ng/mL). The estimated prevalence of vitamin D deficiency and insufficiency among all children in JECS were 25.4% (95% CI, 24.1–26.7%) and 50.9% (95% CI, 49.4–52.4%). Vitamin D deficiency was found in 22.9% of boys and 26.5% of girls. Median serum 25(OH) D concentrations were lower among participants measured during winter and spring than among those measured in summer and autumn. The highest rate of vitamin D deficiency was observed in Hokkaido, the northernmost prefecture of Japan. Conclusion We analyzed data on serum 25(OH) D levels from a birth cohort study and found that vitamin D deficiency and insufficiency are very common among 2-year-old Japanese children. Sex, season, and latitude affect serum 25(OH) D concentrations.Limin YangMiori SatoMayako Saito-AbeMakoto IraharaMinaho NishizatoHatoko SasakiMizuho KonishiKazue IshitsukaHidetoshi MezawaKiwako Yamamoto-HanadaYukihiro Ohyafor the Japan Environment and Children’s Study (JECS) Group)BMCarticle25-Hydroxyvitamin DVitamin DDeficiencyInsufficiencyChildrenCohortPediatricsRJ1-570ENBMC Pediatrics, Vol 21, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic 25-Hydroxyvitamin D
Vitamin D
Deficiency
Insufficiency
Children
Cohort
Pediatrics
RJ1-570
spellingShingle 25-Hydroxyvitamin D
Vitamin D
Deficiency
Insufficiency
Children
Cohort
Pediatrics
RJ1-570
Limin Yang
Miori Sato
Mayako Saito-Abe
Makoto Irahara
Minaho Nishizato
Hatoko Sasaki
Mizuho Konishi
Kazue Ishitsuka
Hidetoshi Mezawa
Kiwako Yamamoto-Hanada
Yukihiro Ohya
for the Japan Environment and Children’s Study (JECS) Group)
25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)
description Abstract Background The study aim was to obtain epidemiological data on vitamin D levels for the pediatric population in Japan. We assessed the prevalence of vitamin D deficiency and insufficiency in 2-year-old Japanese children using data from a large ongoing birth cohort study. Methods Data for analysis was obtained from the Japan Environment and Children’s Study (JECS) and a Sub-Cohort Study (SCS) of JECS. We evaluated the children’s serum 25(OH) D levels by 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles, and the rates of vitamin D deficiency or insufficiency. We also presented a weighted prevalence rate for vitamin D deficiency or insufficiency among all children in JECS. Results After excluding children with missing 25(OH)D2 or 25(OH)D3 data, we analyzed 4655 remaining children, of whom 24.7% (95% CI, 23.5–26.0%) had vitamin D deficiency (< 20 ng/mL), and 51.3% (95% CI, 49.8–52.7%) were at risk of vitamin D insufficiency (20–30 ng/mL). The estimated prevalence of vitamin D deficiency and insufficiency among all children in JECS were 25.4% (95% CI, 24.1–26.7%) and 50.9% (95% CI, 49.4–52.4%). Vitamin D deficiency was found in 22.9% of boys and 26.5% of girls. Median serum 25(OH) D concentrations were lower among participants measured during winter and spring than among those measured in summer and autumn. The highest rate of vitamin D deficiency was observed in Hokkaido, the northernmost prefecture of Japan. Conclusion We analyzed data on serum 25(OH) D levels from a birth cohort study and found that vitamin D deficiency and insufficiency are very common among 2-year-old Japanese children. Sex, season, and latitude affect serum 25(OH) D concentrations.
format article
author Limin Yang
Miori Sato
Mayako Saito-Abe
Makoto Irahara
Minaho Nishizato
Hatoko Sasaki
Mizuho Konishi
Kazue Ishitsuka
Hidetoshi Mezawa
Kiwako Yamamoto-Hanada
Yukihiro Ohya
for the Japan Environment and Children’s Study (JECS) Group)
author_facet Limin Yang
Miori Sato
Mayako Saito-Abe
Makoto Irahara
Minaho Nishizato
Hatoko Sasaki
Mizuho Konishi
Kazue Ishitsuka
Hidetoshi Mezawa
Kiwako Yamamoto-Hanada
Yukihiro Ohya
for the Japan Environment and Children’s Study (JECS) Group)
author_sort Limin Yang
title 25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)
title_short 25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)
title_full 25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)
title_fullStr 25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)
title_full_unstemmed 25-Hydroxyvitamin D levels among 2-year-old children: findings from the Japan environment and Children’s study (JECS)
title_sort 25-hydroxyvitamin d levels among 2-year-old children: findings from the japan environment and children’s study (jecs)
publisher BMC
publishDate 2021
url https://doaj.org/article/abad2f05cf204aaa897f3daab4dc5395
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