Differential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan

Peter Deng Tong, Christine Atuhairwe, Ivan Mugisha Taremwa Clarke International University, Kampala, UgandaCorrespondence: Ivan Mugisha Taremwa Tel +256 774346368Email imugisha@ymail.comAim/Objective: This study explored the caregivers’ self-reported determinants of antiretroviral therapy...

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Autores principales:	Tong PD, Atuhairwe C, Taremwa IM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	art adherence children under five hiv caregivers al-sabah south sudan Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/abb08848a26740798e0beb8bbc2c4cd8
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spelling	oai:doaj.org-article:abb08848a26740798e0beb8bbc2c4cd82021-12-02T09:46:55ZDifferential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan1179-1373https://doaj.org/article/abb08848a26740798e0beb8bbc2c4cd82020-05-01T00:00:00Zhttps://www.dovepress.com/differential-self-reported-determinants-to-antiretroviral-therapy-adhe-peer-reviewed-article-HIVhttps://doaj.org/toc/1179-1373Peter Deng Tong, Christine Atuhairwe, Ivan Mugisha Taremwa Clarke International University, Kampala, UgandaCorrespondence: Ivan Mugisha Taremwa Tel +256 774346368Email imugisha@ymail.comAim/Objective: This study explored the caregivers’ self-reported determinants of antiretroviral therapy (ART) adherence among children under five years living with human immunodeficiency virus (HIV) infection attending Al-Sabah Hospital, South Sudan.Methods: A cross-sectional study of 126 caregivers of HIV-infected children under five years was conducted at Al-Sabah Hospital, South Sudan. Data were collected using an interviewer-administered questionnaire. The self-reported adherence was measured as a binary variable using binary logistic regression. Only variables that were significant at bivariate analysis were analyzed at multivariate level and interpreted using the odds ratios (p< 0.05).Results: Out of 126 caregivers with HIV-infected children, 38 (30.2%) did not adhere to ART. Of the proportion that adhered to ART (88, 69.8%), 49 (55.7%) were male. Most of the children (52, 59.1%) were above two years, but under five years. Fifty (56.8%) of those who adhered had completed 3 months on ART, and the majority were at WHO stage-1 of HIV infection. Analysis of the determinants indicated that children’s duration on ART (p=0.001), type of ART regimen (single, double or triple therapy) (p=0.065), type of work done by the caregiver to earn a living (p-value 0.003), time a child was initiated on ART (p=0.002), caregiver–child relationship (p=0.002), caregiver-spousal support (p=0.019), type of support obtained whether monetary or not (p=0.000), when the child was started on ART (p=0.004), the person administering ART (p=0.010), the type of ARVs administered (p=0.001), the caregiver detecting ART side effects (p=0.000), types of adverse effects suffered by the child (p=0.043), time of receiving ART (p=0.047), use of western medicine (p=0.043), healthcare cadre (p=0.002), the kind of attention the healthcare provider offered (p=0.015), and improvements in quality of HIV services (p=0.001) were significantly associated with ART adherence.Conclusion: The study findings indicated that ART adherence among HIV-infected children under five years was suboptimal. This will necessitate continuous engagement and education of caregivers on the prominence of adhering to ART.Keywords: ART adherence, children under five, HIV, caregivers, Al-Sabah, South SudanTong PDAtuhairwe CTaremwa IMDove Medical Pressarticleart adherencechildren under fivehivcaregiversal-sabahsouth sudanImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol Volume 12, Pp 175-186 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	art adherence children under five hiv caregivers al-sabah south sudan Immunologic diseases. Allergy RC581-607
spellingShingle	art adherence children under five hiv caregivers al-sabah south sudan Immunologic diseases. Allergy RC581-607 Tong PD Atuhairwe C Taremwa IM Differential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan
description	Peter Deng Tong, Christine Atuhairwe, Ivan Mugisha Taremwa Clarke International University, Kampala, UgandaCorrespondence: Ivan Mugisha Taremwa Tel +256 774346368Email imugisha@ymail.comAim/Objective: This study explored the caregivers’ self-reported determinants of antiretroviral therapy (ART) adherence among children under five years living with human immunodeficiency virus (HIV) infection attending Al-Sabah Hospital, South Sudan.Methods: A cross-sectional study of 126 caregivers of HIV-infected children under five years was conducted at Al-Sabah Hospital, South Sudan. Data were collected using an interviewer-administered questionnaire. The self-reported adherence was measured as a binary variable using binary logistic regression. Only variables that were significant at bivariate analysis were analyzed at multivariate level and interpreted using the odds ratios (p< 0.05).Results: Out of 126 caregivers with HIV-infected children, 38 (30.2%) did not adhere to ART. Of the proportion that adhered to ART (88, 69.8%), 49 (55.7%) were male. Most of the children (52, 59.1%) were above two years, but under five years. Fifty (56.8%) of those who adhered had completed 3 months on ART, and the majority were at WHO stage-1 of HIV infection. Analysis of the determinants indicated that children’s duration on ART (p=0.001), type of ART regimen (single, double or triple therapy) (p=0.065), type of work done by the caregiver to earn a living (p-value 0.003), time a child was initiated on ART (p=0.002), caregiver–child relationship (p=0.002), caregiver-spousal support (p=0.019), type of support obtained whether monetary or not (p=0.000), when the child was started on ART (p=0.004), the person administering ART (p=0.010), the type of ARVs administered (p=0.001), the caregiver detecting ART side effects (p=0.000), types of adverse effects suffered by the child (p=0.043), time of receiving ART (p=0.047), use of western medicine (p=0.043), healthcare cadre (p=0.002), the kind of attention the healthcare provider offered (p=0.015), and improvements in quality of HIV services (p=0.001) were significantly associated with ART adherence.Conclusion: The study findings indicated that ART adherence among HIV-infected children under five years was suboptimal. This will necessitate continuous engagement and education of caregivers on the prominence of adhering to ART.Keywords: ART adherence, children under five, HIV, caregivers, Al-Sabah, South Sudan
format	article
author	Tong PD Atuhairwe C Taremwa IM
author_facet	Tong PD Atuhairwe C Taremwa IM
author_sort	Tong PD
title	Differential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan
title_short	Differential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan
title_full	Differential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan
title_fullStr	Differential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan
title_full_unstemmed	Differential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan
title_sort	differential self-reported determinants to antiretroviral therapy adherence: findings from caregivers of children under five years living with human immunodeficiency virus infection attending al-sabah hospital, south sudan
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/abb08848a26740798e0beb8bbc2c4cd8
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Differential Self-Reported Determinants to Antiretroviral Therapy Adherence: Findings from Caregivers of Children Under Five Years Living with Human Immunodeficiency Virus Infection Attending Al-Sabah Hospital, South Sudan

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